Evidence map›Paper›PMID 41158957›Full record

ReviewThe Lancet regional health. Western Pacific2025

Large language models and global health equity: a roadmap for equitable adoption in LMICs.

Haichao Chen, Dian Zeng, Yiming Qin, Zeyue Fan, Faye Ng Yu Ci, David C Klonoff, John S Ji, Shuyang Zhang, Kwesi Nyan Amissah-Arthur, Michelle María Jiménez de Tavárez and 6 more

Abstract readReview
In one paragraph

Review in The Lancet regional health. Western Pacific, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Redefining lightweight vision models for healthcare AI.Frontiers in artificial intelligence · 2026
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Haichao ChenTsinghua Medicine, Tsinghua University, Beijing, China.
Dian ZengTsinghua Medicine, Tsinghua University, Beijing, China.
Yiming QinTsinghua Medicine, Tsinghua University, Beijing, China.
Zeyue FanTsinghua Medicine, Tsinghua University, Beijing, China.
Faye Ng Yu CiYong Loo Lin School of Medicine, National University of Singapore, Singapore.
David C KlonoffDiabetes Research Institute, Mills-Peninsula Medical Center, San Mateo, CA, USA.
John S JiVanke School of Public Health, Tsinghua University, Beijing, China.
Shuyang ZhangRare Disease Medical Center; Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Science, Beijing, China.
Kwesi Nyan Amissah-ArthurOphthalmology Unit, Department of Surgery, Korle Bu Teaching Hospital, College of Health Sciences, School of Medicine and Dentistry, University of Ghana, Accra, Ghana.
Michelle María Jiménez de TavárezSchool of Medicine, Pontificia Universidad Católica Madre y Maestra (PUCMM), Santiago, Dominican Republic.
Saleha MasoodIRC for Finance and Digital Economy, King Fahd University of Petroleum & Minerals, Dhahran, 31261, Saudi Arabia.
Phuoc Van LeCollege of Health Sciences, VinUniversity, Hanoi, Viet Nam.
Pearse A KeaneNIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust, London, UK.
Bin ShengDepartment of Computer Science and Engineering, Shanghai Jiao Tong University, Shanghai, China.
Tien Yin WongTsinghua Medicine, Tsinghua University, Beijing, China.
Yih Chung ThamSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Large language models (LLMs) have been proposed to address global health inequity by providing accessible and high-quality health care, particularly in low- and middle-income countries (LMICs). However, despite the early enthusiasm following the release of GPT, development and deployment of LLMs have remained heavily concentrated in high-income countries (HIC), raising concerns that such technology may worsen existing health disparities instead of alleviating them. The most recent LLMs, which include features such as lower cost, and open-source framework, show promise in rebalancing LLMs' benefits worldwide. In this viewpoint, we examine the current challenges and imbalance in LLM deployment across global regions, identify the key barriers to adoption in LMICs, assess current LLMs' advances and the new opportunities they bring to global health equity. We also propose a five-dimensional roadmap-focusing on people, products, platforms, processes, and policies-to advance LLMs' equitable adoption in LMIC and improve inclusive progress in global health. Funding: National Key R&D Program (Grant No: 2022YFC2502800); National Natural Science Fund of China (Grant No: 82388101); Beijing Natural Science Foundation (Grant No: IS23096).

Indexed as

Health equityLarge language modelsLow- and middle-income countries

Identifiers

PMID41158957
PMCPMC12556221

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.