Evidence map›Paper›PMID 41158920›Full record

ArticleCureus2025

Beyond the Bruise: Unmasking Disseminated Intravascular Coagulation in Alcohol-Related Presentations.

Sri Amarnath Mathiyalagan, Aemon Fatima, Syeda Safa Sadiya, Lunik Sarder

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sri Amarnath MathiyalaganEmergency Medicine, Barking, Havering and RedBridge University Hospitals National Health Service (NHS) Trust, London, GBR.
Aemon FatimaEmergency Medicine, Barking, Havering and RedBridge University Hospitals National Health Service (NHS) Trust, London, GBR.
Syeda Safa SadiyaEmergency Medicine, Barking, Havering and RedBridge University Hospitals National Health Service (NHS) Trust, London, GBR.
Lunik SarderEmergency Medicine, Barking, Havering and RedBridge University Hospitals National Health Service (NHS) Trust, London, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disseminated intravascular coagulation (DIC) is a rare but life-threatening complication encountered in the emergency department (ED). It results from widespread activation of coagulation pathways, leading to simultaneous thrombosis and consumption of clotting factors, often culminating in severe bleeding and multi-organ failure. We report the case of a 39-year-old female with alcohol-related cirrhosis and autoimmune hepatitis who presented to the ED with a minor head injury and active bleeding from a groin ulcer. Her initial evaluation was confounded by alcohol intoxication and suspicion of domestic violence due to multiple bruises. Only after a delayed laboratory assessment was a diagnosis of DIC confirmed in the context of decompensated chronic liver disease with hepatic encephalopathy. She was treated with blood products and discharged with follow-up in the hepatology department. This case illustrates the diagnostic challenges of distinguishing trauma-related bruising from systemic coagulopathy in alcohol-related presentations. It emphasizes the importance of maintaining a high index of suspicion for DIC in cirrhotic patients, the role of the International Society on Thrombosis and Haemostasis DIC score, and the risks of diagnostic overshadowing in the ED. Early recognition and multidisciplinary intervention can significantly improve patient outcomes.

Indexed as

alcohol intoxication and traumaalcohol-related liver disease (arld)bruising differential diagnosiscirrhotic coagulopathydiagnostic overshadowingdisseminated intravascular coagulation (dic)isth dic scoreovert dic vs cirrhotic coagulopathy

Identifiers

PMID41158920
PMCPMC12558426

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.