Evidence map›Paper›PMID 41158905›Full record

ArticleCureus2025

Autism Spectrum Disorder and Temporal Lobe Epilepsy in a Physician: A Self-Reported Case of Neuropsychiatric and Functional Adaptations.

Ixequi Luna-Mendoza, Enrique Torres-Rasgado, José Aurelio Cerón-Morales

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ixequi Luna-MendozaFaculty of Medicine, Benemérita Universidad Autónoma de Puebla, Puebla, MEX.
Enrique Torres-RasgadoDepartment of Biostatistics, Benemérita Universidad Autónoma de Puebla, Puebla, MEX.
José Aurelio Cerón-MoralesDepartment of Neurology, Hospital Puebla, Puebla, MEX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While the comorbidity of autism spectrum disorder (ASD) and epilepsy is well-documented, first-person accounts from physician-patients remain scarce. This report bridges that gap, offering both clinical and functional insights into the lived experience of this dual diagnosis. We detail the case of a 28-year-old physician, a recent medical school graduate, with confirmed ASD level 1 and structural temporal lobe epilepsy (TLE), alongside generalized anxiety disorder and major depressive disorder. The clinical picture is defined by a pronounced sensory hyper-reactivity and a lowered seizure threshold, leading to discognitive and generalized seizures often triggered by sensory or social overload. His management has required a coordinated, multidisciplinary regimen of antiepileptic and psychotropic medications. Our discussion integrates clinical data with a phenomenological perspective. The synergy between ASD and TLE appears to forge a distinct neurobiological profile that demands holistic treatment. The author's development of functional adaptation strategies, a process of translating neurotypical demands into a neurodivergent operational framework, proved essential for navigating the rigors of medical education. This case illustrates that high professional achievement is attainable for individuals with complex neurodevelopmental comorbidities. It also makes a case for a paradigm shift in medicine and academia toward genuine neuro-inclusion, one that moves beyond simple accommodation to foster environments that truly value neurological diversity.

Indexed as

autism spectrum disorder (asd)clinical anxietyclinical case reportclinical depressionelectroencephalography (eeg)neurodiversityneuroimaging biomarkersnuclear magnetic resonancesocial adaptationtemporal lobe epilepsy

Identifiers

PMID41158905
PMCPMC12558430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.