Evidence map›Paper›PMID 41158904›Full record

ArticleCureus2025

Veno-Venous Extracorporeal Membrane Oxygenation (VV-ECMO) as Treatment for Transfusion-Related Acute Lung Injury.

Steven Douedi, Ashraf Sliem, Mihir Odak, Muhammad Raza, Jonathan Stoll, Joseph Lee

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Steven DouediCardiology, Deborah Heart and Lung Center, Browns Mills, USA.
Ashraf SliemInternal Medicine, Hackensack Meridian Health (HMH) Southern Ocean Medical Center, Manahawkin, USA.
Mihir OdakCardiology, Deborah Heart and Lung Center, Browns Mills, USA.
Muhammad RazaCardiology, Deborah Heart and Lung Center, Browns Mills, USA.
Jonathan StollCritical Care, Deborah Heart and Lung Center, Browns Mills, USA.
Joseph LeeCritical Care, Deborah Heart and Lung Center, Browns Mills, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transfusion-related acute lung injury (TRALI) manifests as acute lung injury and hypoxemia occurring several hours after transfusion. While treatment typically involves cessation of the transfusion and supportive measures, severe cases may necessitate mechanical ventilation, including the initiation of veno-venous extracorporeal membrane oxygenation (VV-ECMO). In this case, we present a severe instance of TRALI after a blood transfusion during a femoral endarterectomy. The patient's condition deteriorated intra-operatively post-transfusion, marked by worsening hypoxia and ventilator dyssynchrony, necessitating increased sedation, paralytics, and inhaled nitric oxide. With the patient's respiratory status continuing to decline, VV-ECMO was initiated, resulting in complete recovery of lung function. Our report underscores the rare recovery of TRALI with ECMO, highlighting its efficacy during the acute phase of a transfusion reaction.

Indexed as

blood transfusion reactionrespiratory failuretacotransfusion related acute lung injuryvv ecmo

Identifiers

PMID41158904
PMCPMC12558368

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.