Evidence map›Paper›PMID 41158900›Full record

ArticleCureus2025

A Shocking Complication: Right Ventricular Pacemaker Lead Perforation Presenting With Intractable Hiccups.

Jeremy M Williams, Melville C O'Brien, Pramod Reddy

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jeremy M WilliamsInternal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Melville C O'BrienInternal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Pramod ReddyInternal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Right ventricular (RV) lead perforation is a rare but potentially life-threatening complication after pacemaker implantation, with clinical presentations ranging from asymptomatic to severe hemodynamic compromise. Early diagnosis is challenging due to the heterogeneity of symptoms and overlap with other conditions. We present a unique case of a 60-year-old man who presented with intractable hiccups two days after dual-chamber pacemaker implantation. Initial workup was unrevealing; however, persistent symptoms prompted further review of imaging, which revealed RV lead perforation with migration into the left anterior chest wall. The patient underwent successful extraction and repositioning of the lead, resulting in the resolution of symptoms. This case highlights the diagnostic challenge posed by atypical presentations of RV lead perforation, such as persistent hiccups resulting from phrenic nerve or diaphragmatic irritation. Computed tomography is the most sensitive non-invasive diagnostic tool, but a high index of suspicion is essential for timely diagnosis and management. Early intervention is critical to prevent severe complications.

Indexed as

cardiac device lead migrationct (computed tomography) imagingintractable hiccupspacemaker lead complicationright ventricular lead perforation

Identifiers

PMID41158900
PMCPMC12554986

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.