ArticleAnesthesiology research and practice2025
Comparison of Emergence Delirium in Patients Undergoing Laparoscopic Cholecystectomy With High or Low Fresh Gas Flow During Anesthesia: A Prospective Randomized Double-Blind Study.
Article in Anesthesiology research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Comparison of Emergence Delirium in Patients Undergoing Laparoscopic Cholecystectomy With High or Low Fresh Gas Flow During Anesthesia: A Prospective Randomized Double-Blind Study.Anesthesiology research and practice · 2025Article
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3 authors.
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Abstract
Context: Cause of "emergence delirium" (ED) after general anesthesia with volatile anesthetics in adults remains unclear. While low "fresh gas flow" (FGF) is integral to current anesthesia practice, there is limited literature about FGF's role in ED. Aims: To compare ED in patients receiving high or low FGF during anesthesia with sevoflurane while undergoing laparoscopic cholecystectomy for gallstone disease. Settings and Design: Prospective randomized double-blind study. Methods and Materials: One hundred American Society of Anesthesiologists (ASA) I and II patients, aged 18-50 years, were randomized to a low FGF or high FGF group of 50 patients each. After preoxygenation with 100% oxygen for 3 min, patients were induced. The low FGF group received 4 L for 5 min, followed by 1 L till the end, while the high FGF group received 4 L throughout. Sevoflurane, nitrous oxide, and oxygen (N Statistical Analysis Used: Student's Results: Postoperative lactate was significantly higher in the low FGF group compared with the high FGF group (1.49 ± 0.69 vs. 1.05 ± 0.54 mmol/L, Conclusions: ED and lactate levels were significantly higher in patients receiving low FGF compared to high FGF during anesthesia.
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