ArticleFrontiers in pediatrics2025
Pediatric tonsillar synovial sarcoma: extremely rare case report.
Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Synovial sarcoma (SS) is a malignant tumor characterized by partial epithelial differentiation. While SS predominantly affects older children and young adults, it can arise in nearly any anatomical region. Its occurrence in the tonsil, particularly in the pediatric population, is extremely rare, with only one other case reported in the literature. This rarity poses diagnostic challenges, as its symptoms often resemble more common conditions such as a peritonsillar abscess. Reporting such cases is crucial to expanding the understanding of SS, refining diagnostic approaches, and guiding treatment strategies. This case offers valuable insights into the management of SS in atypical locations. Case presentation: We report the second documented case of pediatric tonsillar synovial sarcoma (SS). The patient, a 5-year-old girl, presented with a 1.5-month history of persistent fever and dysphagia. Radiological examinations revealed a mass originating from the right palatine tonsil, causing irregular narrowing of the oropharyngeal lumen, initially suspected to be a peritonsillar abscess. An incisional biopsy of the right tonsil was performed, and histopathological analysis confirmed the diagnosis of biphasic SS. The patient underwent six cycles of chemotherapy, resulting in significant tumor regression by the 6th month of treatment. This case underscores the necessity of a multidisciplinary approach, combining surgery and chemotherapy, in managing rare tumors. Conclusions: This case highlights the importance of considering rare malignancies like synovial sarcoma in the differential diagnosis of atypical tonsillar masses, especially in pediatric patients with persistent symptoms. The successful outcome achieved through a multidisciplinary approach emphasizes the need for coordinated care in managing such complex tumors. This case contributes valuable insights to the limited literature on pediatric tonsillar SS and may guide future diagnostic and therapeutic strategies for similar cases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.