ArticleEuropean heart journal. Imaging methods and practice2025
Functional and morphological determinants of left ventricular fibrosis in patients with mitral annular disjunction in cardiac magnetic resonance imaging.
Article in European heart journal. Imaging methods and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Mitral Annular Disjunction: Form, Force, and Function.JACC. Case reports · 2026Article
- Predictors of Left Ventricular Fibrosis in Mitral Annular Disjunction: Cardiac Magnetic Resonance Imaging Study.Echocardiography (Mount Kisco, N.Y.) · 2026Article
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Authors and funding
11 authors.
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Abstract
Aims: The study investigates determinants of left ventricular (LV) fibrosis in patients with inferolateral mitral annular disjunction (MAD). Methods and results: This single centre retrospective cohort study included 111 patients [median age 52 years (25th-75th percentile 36-69), 47% female] with inferolateral MAD that underwent cardiac magnetic resonance imaging. Mid-myocardial replacement fibrosis of the basal inferolateral LV wall was present in 27 (24%) patients. Patients with fibrosis were older [63.0 years (25th-75th percentile 53.0-70.0) vs. 47.5 years (25th-75th percentile 34.0-67.5), Conclusion: Age and accelerated longitudinal motion of the basal inferolateral LV segment are independent determinants of replacement fibrosis of the basal inferolateral wall in patients with MAD. The presence of bileaflet MVP and MAD size are significantly associated with this accelerated movement pattern.
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