ReviewFrontiers in microbiology2025
Microbial infection and treatment strategies in cancer patients.
Review in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Molecular studies on the impact of microbiome on anticancer drug resistance.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The interplay between microbes and cancer has garnered significant attention in life sciences. Clinically, microbial infections in cancer patients are common complications and one of the major causes of mortality. Cancer patients often experience compromised immune defenses, and conventional therapies-including radiotherapy, chemotherapy, and invasive surgery-further diminish their resistance to pathogens. Emerging evidence indicates that intratumoral microbes and their interactions with the tumor microenvironment exacerbate cancer cell proliferation, drug resistance, metastasis, and poor prognosis. However, complex multidrug regimens increase patient burden and reduce compliance. This necessitates the development of single agents with dual anticancer and antimicrobial properties. Promisingly, naturally derived compounds and synthetic chemicals exhibit such dual functionalities. This review introduces microbial contributions to oncogenesis and analyzes molecular targets of dual-function agents, proposing their potential as novel therapeutics to improve clinical outcomes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.