Evidence map›Paper›PMID 41158756›Full record

ArticleGenes & diseases2026

Druggable target ATAD2 enhances the malignant progression and cooperates with E2F1 to up-regulate PDK1 expression in glioma.

Shenghua Zhuo, Liangwang Yang, Zhimin Chen, Shenbo Chen, Shuo Yang, Taixue Chen, Wen-Shu Wu, Kai Wang, Kun Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes & diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shenghua ZhuoInternational Center for Aging and Cancer, Department of Neurosurgery, The First Affiliated Hospital of Hainan Medical University (Hainan Academy of Medical Sciences), Haikou, Hainan 571199, China.
Liangwang YangInternational Center for Aging and Cancer, Department of Neurosurgery, The First Affiliated Hospital of Hainan Medical University (Hainan Academy of Medical Sciences), Haikou, Hainan 571199, China.
Zhimin ChenDepartment of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China.
Shenbo ChenInternational Center for Aging and Cancer, Department of Neurosurgery, The First Affiliated Hospital of Hainan Medical University (Hainan Academy of Medical Sciences), Haikou, Hainan 571199, China.
Shuo YangInternational Center for Aging and Cancer, Department of Neurosurgery, The First Affiliated Hospital of Hainan Medical University (Hainan Academy of Medical Sciences), Haikou, Hainan 571199, China.
Taixue ChenInternational Center for Aging and Cancer, Department of Neurosurgery, The First Affiliated Hospital of Hainan Medical University (Hainan Academy of Medical Sciences), Haikou, Hainan 571199, China.
Wen-Shu WuInternational Center for Aging and Cancer, Department of Neurosurgery, The First Affiliated Hospital of Hainan Medical University (Hainan Academy of Medical Sciences), Haikou, Hainan 571199, China.
Kai WangInternational Center for Aging and Cancer, Department of Neurosurgery, The First Affiliated Hospital of Hainan Medical University (Hainan Academy of Medical Sciences), Haikou, Hainan 571199, China.
Kun YangInternational Center for Aging and Cancer, Department of Neurosurgery, The First Affiliated Hospital of Hainan Medical University (Hainan Academy of Medical Sciences), Haikou, Hainan 571199, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gliomas are characterized by high mortality and disability rates. Cancer-testis antigens (CTAs) are among the most promising therapeutic targets for combating cancer. While several CTAs have been associated with the development and progression of gliomas, the role of ATPase family AAA domain-containing protein 2 (ATAD2) in this context has not been thoroughly investigated. In this study, both

Indexed as

ATAD2Cancer-testis antigenE2F1GliomaPDK1

Identifiers

PMID41158756
PMCPMC12555781

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.