Evidence map›Paper›PMID 41158683›Full record

ReviewFrontiers in plant science2025

Different strategies of altering the cell wall to study the impact that these introduced changes have on plant resistance to pathogens.

Megan F DeTemple, Olga A Zabotina

Abstract readReview
In one paragraph

Review in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Megan F DeTempleRoy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA, United States.
Olga A ZabotinaRoy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cell wall (CW) plays many vital roles in plant fitness, ranging from plant development to defense against pathogens. There are many strategies used to make modifications to the CW and observe the consequences it has on plant development, physiology, and resistance to biotic and abiotic stresses. The most common methods used to change the CW include altering CW synthesizing gene expression by producing gene knockouts or overexpression lines, treating with CW enzyme inhibitors, applying exogenous hydrolases, and expressing CW degrading enzymes (CWDEs) in the plant. Alterations in the CW can change plant responses to pathogens through a variety of mechanisms including inducing plant immune pathways, eliciting a variety of PTI responses or by making the CW more resistant to pathogen infection. This review will highlight the insights gained about CW-mediated resistance and the function of each type of polysaccharide in pathogenesis grouped by each CW-modifying technique. Finally, the different advantages and disadvantages of these approaches will be discussed.

Indexed as

cell wallcell wall-degrading enzymespathogenesisplant defenseplant immune signaling

Identifiers

PMID41158683
PMCPMC12555068

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.