Evidence map›Paper›PMID 41158621›Full record

ReviewFrontiers in endocrinology2025

Sleep patterns in adults and children with less common forms of diabetes.

Marilyn Arosemena, Maria V Salguero, Siri Atma W Greeley, Rochelle N Naylor, Esra Tasali, Louis H Philipson

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marilyn ArosemenaTexas Diabetes Institute - University Health, University of Texas Health San Antonio, San Antonio, TX, United States.
Maria V SalgueroPediatric Endocrinology, Advocate Christ Medical Center, Oak Lawn, IL, United States.
Siri Atma W GreeleyDepartment of Pediatrics, The University of Chicago, Chicago, IL, United States.
Rochelle N NaylorDepartment of Pediatrics, The University of Chicago, Chicago, IL, United States.
Esra TasaliDepartment of Medicine, The University of Chicago, Chicago, IL, United States.
Louis H PhilipsonDepartment of Pediatrics, The University of Chicago, Chicago, IL, United States.

Funding

Pilot and Feasibility ProgramP30DK020595 · NIDDK · UNIVERSITY OF CHICAGO · PI Raghavendra G Mirmira · 2013 to 2026
$20.9M
Monogenic Diabetes: Next Generation Diagnosis, Treatment and ComplicationsR01DK104942 · NIDDK · UNIVERSITY OF CHICAGO · PI GREELEY, SIRI ATMA W., PHILIPSON, LOUIS H. · 2016 to 2024
$4.7M
Technology-Supported Treatment of Sleep Apnea in PrediabetesR01DK120312 · NIDDK · UNIVERSITY OF CHICAGO · PI TASALI, ESRA · 2019 to 2023
$3.9M
Mechanisms of Prediabetic States in Obstructive Sleep ApneaR01HL146127 · NHLBI · UNIVERSITY OF CHICAGO · PI TASALI, ESRA · 2019 to 2023
$3.9M
Sleep Extension: A Novel Intervention for Weight Loss in Young AdultsR01DK136214 · NIDDK · UNIVERSITY OF CHICAGO · PI Esra Tasali · 2023 to 2026
$2.8M
Obstructive sleep apnea and glycemic dysregulation in adults with type 1 diabetesR01HL174685 · NHLBI · UNIVERSITY OF CHICAGO · PI Esra Tasali · 2024 to 2026
$2.1M
NHLBI NIH HHS R01 HL146127NHLBI NIH HHS R01 HL174685NIDDK NIH HHS P30 DK002059NIDDK NIH HHS P30 DK020595NIDDK NIH HHS R01 DK104942NIDDK NIH HHS R01 DK120312NIDDK NIH HHS R01 DK136214NIDDK NIH HHS T32 GM000719
6 · The paper itself

Abstract

Objective: To review the current evidence on sleep patterns in relation to glucose control in adults and children with type 1 diabetes (T1DM) and monogenic diabetes. Methods: We searched for the literature pertaining to T1DM and monogenic diabetes with reported sleep patterns, along with glycemic control, in PubMed. This review aimed to examine the current evidence on the relationship between sleep patterns and diabetes management and possible mediating mechanisms for this relationship in adults and children with T1DM and monogenic diabetes. We reviewed articles published from inception until 2023. Results: Twenty-five clinical studies met the eligibility criteria and were included. Children with T1DM with higher sleep variability had higher glucose levels, and those with higher glucose variability had more sleep disruptions. Comparing children with suboptimal [hemoglobin A1c (HbA1c) ≥ 7.5%] and optimal glucose control, those with suboptimal control had shorter sleep duration. There was no higher prevalence of obstructive sleep apnea (OSA) in children with T1DM compared to controls, but in T1DM, those who had OSA had higher glucose levels. Adults with T1DM had a high prevalence of poor sleep quality and were also sleeping less than the recommended hours for their age. Poor sleep quality and short sleep duration correlated with higher glycemic variability. First-generation automated insulin delivery systems did not improve sleep patterns in T1DM, but other strategies, including coaching and counseling, proved to be effective. Monogenic diabetes data also suggest poor sleep quality, short sleep duration, and high rates of sleep apnea. Conclusion: T1DM subjects seem to have worse sleep patterns, especially those with suboptimal glucose control. Monogenic diabetes data are limited, but they also suggest poor sleep patterns. Rigorous interventional studies are needed to further elucidate the sleep-diabetes relationship. Future research could provide insights into strategies that could effectively improve sleep in people living with diabetes.

Indexed as

Diabetes Mellitus, Type 1SleepSleep Wake DisordersAdultBlood GlucoseChildGlycated HemoglobinHumansBlood GlucoseGlycated HemoglobinMODY (mature onset diabetes of the young)monogenic diabetes mellitusobstructive sleep apneasleeptype 1 diabetes mellitus

Identifiers

PMID41158621
PMCPMC12554434

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.