Evidence map›Paper›PMID 41158570›Full record

ArticleFrontiers in public health2025

A science-based product regulation: the time has come to reduce toxic emissions to reduce harm.

Michael Kunze, José Roberto Santin, Ursula Kunze

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Michael KunzeCenter of Public Health, Department of Social Medicine, Medical University of Vienna, Vienna, Austria.
José Roberto SantinPost-graduation Program in Pharmaceutical Sciences, Universidade do Vale do Itajaí (UNIVALI), Itajaí, SC, Brazil.
Ursula KunzeCenter of Public Health, Department of Social Medicine, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tobacco control has focused on reducing use, with little emphasis on regulating product toxicity. Articles 9 and 10 of the World Health Organization's Framework Convention on Tobacco Control (FCTC) offer a mechanism to reduce harm by limiting toxic emissions, but implementation has stalled. A science-based regulatory framework is needed to set emission thresholds for toxicants. Inspiration can be found from other regulated sectors, and the initial focus should be on nine priority toxicants strongly linked to tobacco-related disease. An adaptive, evidence-based approach can complement existing strategies and accelerate harm reduction for more than 1 billion people who still smoke. The 11th FCTC Conference of the Parties in 2025 presents an opportunity to revisit the development of a toxicity reduction strategy.

Indexed as

Harm ReductionHazardous SubstancesTobacco ProductsHumansWorld Health OrganizationHazardous SubstancesFCTCregulationtobaccotobacco producttoxicity

Identifiers

PMID41158570
PMCPMC12554685

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.