Evidence map›Paper›PMID 41158526›Full record

ArticleFrontiers in cellular and infection microbiology2025

Clonal transmission and species-specific mechanisms of polymyxin resistance in carbapenem-resistant

Tingting Si, Hang Liu, Peiwen Xia, Na Huang, Shiyu Tang, Yuqiong Li, Qi Han, Yuanyuan Song, Yingyi Liu, Yun Xia

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Risk factors for invasiveFrontiers in cellular and infection microbiology · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tingting SiDepartment of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Hang LiuDepartment of Clinical Laboratory, Institute of Translational Medicine, Renmin Hospital of Wuhan University, Wuhan, China.
Peiwen XiaDepartment of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Na HuangDepartment of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Shiyu TangDepartment of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yuqiong LiDepartment of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Qi HanDepartment of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yuanyuan SongDepartment of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yingyi LiuDepartment of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yun XiaDepartment of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The rapid dissemination of carbapenem-resistant Methods: Antimicrobial susceptibility and resistance genes were analyzed by PCR-based amplification and sequence analysis. Molecular epidemiological characteristics were analyzed using Enterobacterial Repetitive Intergenic Consensus (ERIC)-PCR and multilocus sequence typing (MLST). The gene expression of Results: Thirty PR-CRE isolates, including 21 Conclusion: These findings reveal species-divergent resistance mechanisms to polymyxin, necessitating enhanced surveillance of these high-risk clones, mobile elements, and emergent resistance mechanisms.

Indexed as

Carbapenem-Resistant EnterobacteriaceaeDrug Resistance, Multiple, BacterialEnterobacteriaceae InfectionsPolymyxinsAdultAgedAged, 80 and overAnti-Bacterial AgentsChinaChromosomes, BacterialConjugation, GeneticFemaleHumansMaleMiddle AgedMolecular EpidemiologyAnti-Bacterial AgentsPolymyxinscarbapenem-resistant Enterobacteriaceaeclonal transmissionfusion plasmidMCR-1mgrB inactivationpolymyxin resistance

Identifiers

PMID41158526
PMCPMC12554700

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.