Evidence map›Paper›PMID 41158523›Full record

ArticleFrontiers in cellular and infection microbiology2025

A TtAgo-mediated LAMP System for highly sensitive and specific detection of rotavirus in pediatric diarrheal samples.

Ligong Wang, Linlin Fan, Dan Wang, Qian Ma, Jian Hu, Xiaoqin Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ligong Wang *Department of Clinical Laboratory, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Linlin Fan *Department of Clinical Laboratory, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Dan WangDepartment of Clinical Laboratory, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Qian MaDepartment of Clinical Laboratory, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Jian HuDepartment of Clinical Laboratory, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Xiaoqin WangDepartment of Clinical Laboratory, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rotavirus remains a leading cause of severe pediatric gastroenteritis worldwide, particularly in regions with limited healthcare resources, timely diagnosis is essential for effective patient management and outbreak containment. Loop-mediated isothermal amplification (LAMP) offers rapid nucleic acid amplification under constant temperature, yet classic LAMP assays are prone to false positives from nonspecific amplification products. Here, we present a reverse transcription LAMP (RT-LAMP) assay integrated with

Indexed as

DiarrheaMolecular Diagnostic TechniquesNucleic Acid Amplification TechniquesRotavirusRotavirus InfectionsChildChild, PreschoolFecesHumansInfantRNA, ViralROC CurveSensitivity and SpecificityRNA, ViralAGO (Argonaute)diarrhealLAMP (loop mediated isothermal amplification)pediatricrotavirus (RV)

Identifiers

PMID41158523
PMCPMC12554721

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.