Evidence map›Paper›PMID 41158483›Full record

ReviewERJ open research2025

Bronchiectasis and sinonasal diseases: a narrative review.

Edoardo Simonetta, Alessandro De Angelis, Margherita S Silani, Veronica Polelli, Mattia Nigro, Anna Stainer, Francesco Amati, Andrea Gramegna, Francesca Pirola, Giuseppe Mercante and 3 more

Abstract readReview
In one paragraph

Review in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. The importance of symptoms in bronchiectasis.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Edoardo SimonettaRespiratory Unit, IRCCS Humanitas Research Hospital, Milan, Italy.
Alessandro De AngelisRespiratory Unit, IRCCS Humanitas Research Hospital, Milan, Italy.ORCID https://orcid.org/0009-0004-3544-0361
Margherita S SilaniRespiratory Unit and Cystic Fibrosis Adult Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Veronica PolelliPhysiotherapy Unit, IRCCS Humanitas Research Hospital, Milan, Italy.ORCID https://orcid.org/0009-0006-8095-4251
Mattia NigroRespiratory Unit, IRCCS Humanitas Research Hospital, Milan, Italy.ORCID https://orcid.org/0000-0003-4735-823X
Anna StainerRespiratory Unit, IRCCS Humanitas Research Hospital, Milan, Italy.
Francesco AmatiRespiratory Unit, IRCCS Humanitas Research Hospital, Milan, Italy.
Andrea GramegnaRespiratory Unit and Cystic Fibrosis Adult Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.ORCID https://orcid.org/0000-0003-2315-5737
Francesca PirolaOtorhinolaryngology Head & Neck Surgery Unit, IRCCS Humanitas Research Hospital, Milan, Italy.
Giuseppe MercanteDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.ORCID https://orcid.org/0000-0002-1009-7892
Francesco BlasiRespiratory Unit and Cystic Fibrosis Adult Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.ORCID https://orcid.org/0000-0002-2285-9970
Luca MalvezziDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.
Stefano AlibertiRespiratory Unit, IRCCS Humanitas Research Hospital, Milan, Italy.ORCID https://orcid.org/0000-0002-0090-4531

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bronchiectasis and chronic rhinosinusitis are chronic diseases of the upper and lower respiratory tract characterised by both infective and inflammatory pathways. The two share many clinical, radiological, microbiological and pathophysiological aspects. Bronchiectasis and chronic rhinosinusitis may be characterised by different endotypes, with inflammation driven by either neutrophils and/or eosinophils. Although the two conditions may coexist, the prevalence of their association remains uncertain. To date, few studies have investigated the pathogenetic relationship between these disorders, with ambiguous results obtained in heterogeneous populations. Some findings suggest that patients with both chronic rhinosinusitis and bronchiectasis may have a heavier disease burden consisting of more exacerbations, more debilitating symptoms, higher radiological severity and worse quality of life. In light of this, identification of treatable traits is crucial and patients are likely to benefit from a multidisciplinary approach involving, among others, pulmonologists, ear-nose-throat physicians, respiratory physiotherapists and allergists/immunologists.

Identifiers

PMID41158483
PMCPMC12557435

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.