Evidence map›Paper›PMID 41158482›Full record

ArticleERJ open research2025

Feasibility and diagnostic yield of a photoplethysmography-based arrhythmia screening and integrated management pathway in a COPD outpatient clinic.

Maartje J M Hereijgers, Rachel M J van der Velden, Lauren G Reinders, Zoey Weerts, Sanne Kuijpers, Justin Luermans, Sevasti-Maria Chaldoupi, Kevin Vernooy, Astrid N L Hermans, Rein Posthuma and 3 more

Abstract read
In one paragraph

Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Maartje J M HereijgersDepartment of Cardiology, Maastricht University Medical Centre, Maastricht, the Netherlands.ORCID https://orcid.org/0000-0002-8896-6293
Rachel M J van der VeldenDepartment of Cardiology, Maastricht University Medical Centre, Maastricht, the Netherlands.
Lauren G ReindersDepartment of Cardiology, Maastricht University Medical Centre, Maastricht, the Netherlands.ORCID https://orcid.org/0009-0009-7748-0763
Zoey WeertsDepartment of Cardiology, Maastricht University Medical Centre, Maastricht, the Netherlands.ORCID https://orcid.org/0009-0008-6615-5167
Sanne KuijpersDepartment of Cardiology, Maastricht University Medical Centre, Maastricht, the Netherlands.
Justin LuermansDepartment of Cardiology, Maastricht University Medical Centre, Maastricht, the Netherlands.
Sevasti-Maria ChaldoupiDepartment of Cardiology, Maastricht University Medical Centre, Maastricht, the Netherlands.
Kevin VernooyDepartment of Cardiology, Maastricht University Medical Centre, Maastricht, the Netherlands.
Astrid N L HermansDepartment of Cardiology, Maastricht University Medical Centre, Maastricht, the Netherlands.
Rein PosthumaDepartment of Respiratory Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands.
Frits M E FranssenDepartment of Respiratory Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands.ORCID https://orcid.org/0000-0002-1633-6356
Dominik LinzDepartment of Cardiology, Maastricht University Medical Centre, Maastricht, the Netherlands.
Sami O SimonsDepartment of Respiratory Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands.ORCID https://orcid.org/0000-0002-4296-5076

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Guidelines recommend opportunistic atrial fibrillation (AF) screening in high-risk populations, including COPD patients. This cohort study aimed to evaluate the feasibility and yield of a photoplethysmography (PPG)-based mHealth pathway for AF detection in a COPD outpatient clinic. Methods: COPD patients at Maastricht University Medical Centre+ were invited to participate in a 14-day PPG-based AF screening embedded within the COPD care pathway using their smartphone. Results: Out of 155 invited moderate-to-severe COPD patients, 99 (mean age 66±9 years, 54% female) participated in the AF screening. Adherence (101% (82-123%)) and patient satisfaction (System Usability Score 80.0 (IQR 55.0-92.5)) were high. The PPG-based pathway detected 8 of 99 (8.1%) AF cases (6 new and 2 known AF). Additional cardiac work-up of the six new cases revealed ECG-confirmed AF in two (2.0%) patients and frequent premature beats in three patients. PPG analysis showed additional arrhythmias in 95 of 99 patients (isolated premature beats) and 31 of 99 patients (frequent premature beats), of which 8 (8.0%) patients necessitated additional cardiac analysis. The overall diagnostic yield of PPG-based AF screening was thus 8%, yield of ECG-confirmed new AF was 2% and in 10% of the patients, additional arrhythmias were detected. Of the 99 patients, 12 of 99 (12%) patients needed referral to cardiac work-up. Conclusion: 14-day opportunistic PPG-based, mHealth-supported AF screening is feasible in COPD outpatient care and results in the detection of new AF cases and premature beats. This novel digital approach offers a practical guidance for implementing recommended AF screening and management in COPD patients.

Identifiers

PMID41158482
PMCPMC12557434

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.