ArticleJournal of thoracic disease2025
Comparison of clinical and economic outcomes among patients undergoing lung resection using ECHELON
Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
Background: The use of surgical staplers for lung resection is widespread; however, determining the optimal surgical stapler remains a challenge. This study compared clinical and economic outcomes of the ECHELON™ 3000 Stapler (ECH3000) against its previous generation ECHELON™+ Stapler (ECH+) among patients undergoing lung resection. Methods: This was a retrospective, multi-institutional, comparative cohort study among patients undergoing lung resection using ECH3000 or ECH+ between April 1, 2022 and September 30, 2023 in the Premier Healthcare Database (PHD). The primary outcome was 30-day prolonged air leak (PAL). Secondary outcomes included 30-day bleeding-related complications and all-cause inpatient readmission, and index admission total hospital costs, length of stay (LOS), discharge status, and mortality. Covariate balancing propensity score (CBPS) weighting was used to balance baseline characteristics between groups. The difference in the cumulative incidence (binary outcomes) and mean (continuous outcomes) of study outcomes was calculated using covariate-balanced data. For the primary outcome, the non-inferiority in the difference in the cumulative incidence of 30-day PAL between groups was evaluated using a prespecified non-inferiority margin of 10%. Results: A total of 910 (ECH3000: 277; ECH+: 633) patients met the study eligibility criteria. The cumulative incidences of 30-day PAL were comparable between ECH3000 Conclusions: Among patients undergoing lung resection, ECH3000 had a comparable cumulative incidence of 30-day PAL and a lower cumulative incidence of bleeding-related complications compared to ECH+.
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