ArticleJournal of experimental orthopaedics2025
Higher cost, comparable outcomes: A health economic evaluation of patient-specific instrumentation vs. conventional instrumentation for total knee arthroplasty in a Dutch aging population.
Article in Journal of experimental orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Higher cost, comparable outcomes: A health economic evaluation of patient-specific instrumentation vs. conventional instrumentation for total knee arthroplasty in a Dutch aging population.Journal of experimental orthopaedics · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: The demand for treatment of knee osteoarthritis is rising as the population ages. To optimise outcomes of total knee arthroplasty (TKA), several innovative techniques have been introduced, including patient-specific instrumentation (PSI). While these developments may improve clinical outcomes, they are often associated with higher healthcare costs. The present study aimed to evaluate the long-term cost-utility of PSI compared to conventional instrumentation (CI) for TKA, from a hospital perspective. Methods: A multicenter randomised controlled trial including 180 patients was conducted in 2010, with 45 patients in each treatment arm per center. For the current economic evaluation, data from one participating center ( Results: At final follow-up, 23 patients (26%) were lost due to death ( Conclusion: Both PSI and CI TKA improved quality of life at 5 and 10 years postoperatively. However, PSI incurred higher costs without demonstrating additional clinical benefit. From a hospital perspective, CI remains the more cost-effective approach. Level of Evidence: Level II, retrospective study of an RCT.
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