Evidence map›Paper›PMID 41158182›Full record

ArticleInternational journal of ophthalmology2025

Efficacy, safety and IOP-lowering mechanisms of ultrasound cycloplasty for angle-closure glaucoma.

Guo Liu, Yu-Kai Mao, Nan-Xin Liu, Jun-Kai Tan, Gang Qiao, Zi-Jie Chen, Qiang Li, Qin-Yu Huang, Xiao-Chun Yang, Zi-Jing Wu and 2 more

Abstract read
In one paragraph

Article in International journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Guo LiuMianyang Wanjiang Eye Hospital, Mianyang 621000, Sichuan Province, China.
Yu-Kai MaoDepartment of Ophthalmology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, Zhejiang Province, China.
Nan-Xin LiuXiamen Eye Center, Xiamen Research Center for Eye Diseases and Key Laboratory of Ophthalmology, Xiamen University, Xiamen 361000, Fujian Province, China.
Jun-Kai TanXiamen Eye Center, Xiamen Research Center for Eye Diseases and Key Laboratory of Ophthalmology, Xiamen University, Xiamen 361000, Fujian Province, China.
Gang QiaoMianyang Wanjiang Eye Hospital, Mianyang 621000, Sichuan Province, China.
Zi-Jie ChenXiamen Eye Center, Xiamen Research Center for Eye Diseases and Key Laboratory of Ophthalmology, Xiamen University, Xiamen 361000, Fujian Province, China.
Qiang LiDepartment of Ophthalmology, Shenzhen People's Hospital, The 2nd Clinical Medical College, Jinan University, Shenzhen 518020, Guangdong Province, China.
Qin-Yu HuangXiamen Eye Center, Xiamen Research Center for Eye Diseases and Key Laboratory of Ophthalmology, Xiamen University, Xiamen 361000, Fujian Province, China.
Xiao-Chun YangMianyang Wanjiang Eye Hospital, Mianyang 621000, Sichuan Province, China.
Zi-Jing WuMianyang Wanjiang Eye Hospital, Mianyang 621000, Sichuan Province, China.
Meng XuXiamen Eye Center, Xiamen Research Center for Eye Diseases and Key Laboratory of Ophthalmology, Xiamen University, Xiamen 361000, Fujian Province, China.
Xu-Yang LiuXiamen Eye Center, Xiamen Research Center for Eye Diseases and Key Laboratory of Ophthalmology, Xiamen University, Xiamen 361000, Fujian Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the short-term efficacy and safety of ultrasound cycloplasty (UCP) procedure in Chinese patients with angle-closure glaucoma (ACG), and the mechanisms of its intraocular pressure (IOP) lowering effects.

methodsFifty-six patients (56 eyes) diagnosed with primary and/or secondary ACG were enrolled in this prospective study. Visual acuity, IOP, slit-lamp examinations, structural parameters of anterior segments including anterior chamber depth (ACD), pupillary diameter (PD), anterior chamber area (ACAr), anterior chamber angle (ACAn), and side effects were evaluated. Seven rhesus macaques (

resultsFifty six eyes of 24 male and 32 female patients with an average age of 58.93±15.97 years old were recruited in primary and secondary ACG affected 31 and 25 eyes, respectively. Clinically, the mean IOP was 17.89±7.93 mm Hg (

conclusionUCP is efficient and safe to lower the IOP of patients with ACG. Changed anterior chamber structure and increased aqueous humour outflow

Indexed as

angle-closure glaucomaefficacymechanismssafetyultrasound cycloplasty

Identifiers

PMID41158182
PMCPMC12554540

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.