SynthesisAnnals of medicine2025
Effect of pressure-controlled ventilation-volume guaranteed mode on intraoperative respiratory mechanics, oxygenation and postoperative pulmonary complications: a systematic review and network meta-analysis.
Synthesis in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVentilation strategies during general anesthesia are crucial for optimizing respiratory mechanics, ensuring adequate oxygenation, and minimizing postoperative pulmonary complications (PPCs) in surgical patients. This systematic review and network meta-analysis (NMA) aim to evaluate the effect of pressure controlled volume guaranteed ventilation (PCV-VG) in patients undergoing non-cardiothoracic surgery.
methodsWe selected randomized controlled trials (RCTs) to explore the effect of PCV-VG mode on intraoperative respiratory mechanics, oxygenation and PPCs in surgical patients published in English by searching PubMed, Embase, Web of Science, and the Cochrane from inception to May 2025. The primary outcome was dynamic lung compliance (Cdyn).
resultsFourteen studies with 2263 patients were included. Compared to volume-controlled ventilation (VCV), PCV-VG had higher Cdyn and lower airway peak pressure (Ppeak). For tidal volume (Vt), partial pressure of carbon dioxide in arterial blood (PaCO
conclusionsPCV-VG was superior to VCV in Cdyn and Ppeak, PCV only achieved higher Cdyn than VCV for prone position. The three modes did not differ in Vt, Pmean, PetCO
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