Evidence map›Paper›PMID 41157878›Full record

ReviewProceedings. Biological sciences2025

The olfactory neurobiology and chemical ecology of mosquito attraction to plant nutrient sources.

Melissa Leon Noreña, Sandeep Jandu, John Boyi, Lucia Ibarra Bouzada, Angela Rouyar, Iliano Coutinho Abreu, Fanying Chen, Omar S Akbari, R Jason Pitts, Jeffrey A Riffell

Abstract readReview
In one paragraph

Review in Proceedings. Biological sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Melissa Leon Noreña *Department of Biology, University of Washington, Seattle, WA 98105, USA.
Sandeep Jandu *Department of Biology, University of Washington, Seattle, WA 98105, USA.
John Boyi *Department of Biology, Baylor University, Waco, TX 76798, USA.
Lucia Ibarra BouzadaDepartment of Biology, Baylor University, Waco, TX 76798, USA.
Angela RouyarDepartment of Biology, University of Washington, Seattle, WA 98105, USA.
Iliano Coutinho AbreuSchool of Biological Sciences, Department of Cell and Developmental Biology, UC San Diego, La Jolla, CA 92037, USA.
Fanying ChenSchool of Biological Sciences, Department of Cell and Developmental Biology, UC San Diego, La Jolla, CA 92037, USA.
Omar S AkbariSchool of Biological Sciences, Department of Cell and Developmental Biology, UC San Diego, La Jolla, CA 92037, USA.
R Jason PittsDepartment of Biology, Baylor University, Waco, TX 76798, USA.
Jeffrey A RiffellDepartment of Biology, University of Washington, Seattle, WA 98105, USA.ORCID 0000-0002-7645-5779

Funding

The olfactory basis of locating nectar sugar sources in Aedes aegypti mosquitoesR01AI148300 · NIAID · UNIVERSITY OF WASHINGTON · PI Omar Sultan Akbari, Ronald Jason Pitts · 2021 to 2026
$4.1M
Olfactory modulation of color vision and behavior in mosquitoesR01AI175152 · NIAID · UNIVERSITY OF WASHINGTON · PI Omar Sultan Akbari, Jeffrey A Riffell · 2023 to 2026
$3.2M
NIAID NIH HHS R01 AI148300NIAID NIH HHS R01 AI175152NIH HHS
6 · The paper itself

Abstract

Invasive mosquito species are key vectors of arboviral diseases, like dengue, zika and chikungunya, posing significant public health challenges worldwide. These issues are worsened by urbanization, climate change and insecticide resistance, driving research into new control methods. Adult mosquitoes are attracted to plant nutrient sources essential for flight and reproduction. However, few studies have examined the odours emitted by these sources, and little is known about the olfactory neurobiology of mosquito-plant interactions. This review synthesizes current knowledge on the broad classes of volatile compounds that modulate mosquito behaviour, focusing on the olfactory processes underlying mosquito responses to plant nutrient sources. We also discuss the application of neurogenetic tools for investigating the role of olfactory receptor genes and neural circuits in mosquito ecology. Finally, we explore how insights from these studies can inform and enhance mosquito control strategies, including developing synthetic lures for attractive toxic sugar baits and improved trapping and surveillance technologies. Defining the olfactory receptors, sensory neurons and neural circuits mediating attraction or repellency to plant odours is crucial for optimizing mosquito monitoring and control interventions.

Indexed as

CulicidaeMosquito VectorsPlantsSmellAnimalsMosquito ControlNutrientsOdorantsNutrientschemical ecologymosquitomosquito–plant interactionsnectarodorant receptorolfactionolfactory neurobiologyplant nutrients

Identifiers

PMID41157878
PMCPMC12569477

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.