Evidence map›Paper›PMID 41157623›Full record

ArticleViruses2025

Association Between Serum HBV DNA Levels and CCL-20, CD8a, CXCL-16, and GDF-15 in Patients with Chronic Hepatitis B.

Burak Ezer, Hilal Sena Esen, Selin Ugrakli, Mehmet Sinan Iyisoy, Mehmet Ozdemir

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Burak EzerMedical Microbiology Laboratory, Beyhekim Training and Research Hospital, University of Health Sciences, 42090 Konya, Turkey.ORCID 0000-0003-1217-2080
Hilal Sena EsenDepartment of Medical Microbiology, Faculty of Medicine, Necmettin Erbakan University, 42090 Konya, Turkey.ORCID 0009-0001-8056-6383
Selin UgrakliDepartment of Medical Microbiology, Faculty of Medicine, Necmettin Erbakan University, 42090 Konya, Turkey.ORCID 0000-0001-7210-8377
Mehmet Sinan IyisoyDepartment of Medical Education and Informatics, Faculty of Medicine, Necmettin Erbakan University, 42090 Konya, Turkey.ORCID 0000-0001-5895-9984
Mehmet OzdemirDivision of Medical Virology, Department of Medical Microbiology, Faculty of Medicine, Necmettin Erbakan University, 42090 Konya, Turkey.ORCID 0000-0002-9316-771X

Funding

Scientific Research Project Coordinatorship of the University of Necmettin Erbakan. Project number 24GAP18013
6 · The paper itself

Abstract

The aim of our study is to determine the changes in the biomarkers CXCL-16, CCL-20, GDF-15, and CD8a, which play an immunological role in CHB patients according to viral load to determine their diagnostic potential and to investigate their relationships with hematological parameters and non-invasive fibrosis indices. Our study included 96 chronic hepatitis B patients and 30 healthy individuals as a control group. The patients were divided into three groups based on their serum HBV DNA levels: mild (0-10

Indexed as

Chemokine CXCL16DNA, ViralGrowth Differentiation Factor 15Hepatitis B, ChronicHepatitis B virusAdultBiomarkersFemaleHumansMaleMiddle AgedROC CurveViral LoadBiomarkersChemokine CXCL16DNA, ViralGDF15 protein, humanGrowth Differentiation Factor 15CCL-20CD8achronic hepatitis BCXCL-16GDF-15HBV DNA

Identifiers

PMID41157623
PMCPMC12568015

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.