Evidence map›Paper›PMID 41157610›Full record

ReviewViruses2025

Advances in Prevention, Screening, and Early Detection of HPV-Associated Head and Neck Cancers.

Evangelos Zazas, Panagiota Economopoulou, Ioannis Kotsantis, Anastasios Kyriazoglou, Menelaos G Samaras, Periklis Foukas, Amanda Psyrri

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Evangelos ZazasOncology Department, 2nd Propaedeutic Clinic of Internal Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, Rimini 1, Chaidari, 124 62 Athens, Greece.
Panagiota EconomopoulouOncology Department, 2nd Propaedeutic Clinic of Internal Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, Rimini 1, Chaidari, 124 62 Athens, Greece.
Ioannis KotsantisOncology Department, 2nd Propaedeutic Clinic of Internal Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, Rimini 1, Chaidari, 124 62 Athens, Greece.
Anastasios KyriazoglouOncology Department, 2nd Propaedeutic Clinic of Internal Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, Rimini 1, Chaidari, 124 62 Athens, Greece.
Menelaos G SamarasSecond Department of Pathology, Attikon University Hospital, National and Kapodistrian University of Athens, Rimini 1, Chaidari, 124 62 Athens, Greece.
Periklis FoukasSecond Department of Pathology, Attikon University Hospital, National and Kapodistrian University of Athens, Rimini 1, Chaidari, 124 62 Athens, Greece.
Amanda PsyrriOncology Department, 2nd Propaedeutic Clinic of Internal Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, Rimini 1, Chaidari, 124 62 Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HPV-related head and neck cancers are increasing globally and although they constitute a major public health problem, there are currently no validated screening or early detection methods in widespread clinical use. This review discusses advances in clinical and molecular aspects of prevention, screening, and early detection of HPV-related head and neck cancers (HNCs), such as potential use of HPV blood or saliva seropositivity, RNA biomarkers, liquid biopsy, circulating tumor DNA, and proteomics. In addition to HPV vaccination, public education about vaccination, smoking, and safe sexual practices is warranted. Continued research is warranted to define optimal use and integration of approaches for prevention, screening, and early detection methods of HNCs.

Indexed as

Early Detection of CancerHead and Neck NeoplasmsPapillomaviridaePapillomavirus InfectionsHumansMass Screeningcirculating tumor DNAearly detectionhead and neck cancerHPVHPV serologyliquid biopsyoropharyngeal carcinomapreventionsalivaomicsscreening biomarkers

Identifiers

PMID41157610
PMCPMC12567812

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.