Evidence map›Paper›PMID 41157263›Full record

ArticleLife (Basel, Switzerland)2025

Paroxetine Triggers Inflammatory State on Zebrafish Early Embryonic Development.

Elena Maria Scalisi, Agata Scalisi, Stefania Indelicato, Antonio Salvaggio, Fabiano Capparucci, Roberta Pecoraro, Maria Violetta Brundo

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elena Maria ScalisiDepartment of Biological, Geological and Environmental Science, University of Catania, 95124 Catania, Italy.ORCID 0000-0002-4910-4500
Agata ScalisiDepartment of Biological, Geological and Environmental Science, University of Catania, 95124 Catania, Italy.
Stefania IndelicatoDepartment of Biological, Geological and Environmental Science, University of Catania, 95124 Catania, Italy.
Antonio SalvaggioExperimental Zooprophylactic Institute of Sicily "A. Mirri", 90129 Palermo, Italy.ORCID 0000-0001-6063-9517
Fabiano CapparucciDepartment of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, 98122 Messina, Italy.ORCID 0000-0003-1807-406X
Roberta PecoraroDepartment of Biological, Geological and Environmental Science, University of Catania, 95124 Catania, Italy.ORCID 0000-0003-3293-728X
Maria Violetta BrundoDepartment of Biological, Geological and Environmental Science, University of Catania, 95124 Catania, Italy.ORCID 0000-0001-5146-3564

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paroxetine (PRX) is a common antidepressant, also frequently used by pregnant women to treat depression and anxiety associated with pregnancy; thus, we should increase warnings about its intake. The increased presence of paroxetine in the environment raises concerns about unintended exposure to it, with consequences for embryonic development. However, the effect of PRX on early embryonic development, particularly on the embryonic brain, is still poorly studied, so this study aimed to investigate its toxicological profile on embryonated eggs of

Indexed as

acetylcholinesteraseD. rerioPRXROStoxicity

Identifiers

PMID41157263
PMCPMC12565140

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.