Evidence map›Paper›PMID 41157214›Full record

ArticleLife (Basel, Switzerland)2025

Novel Respiratory Breath Hold Index: A Predictor for Successful Extubation in Mechanically Ventilated Patients, a Prospective Cohort Study.

Arie Soroksky, Gingy Ronen Balmor, Riziny Nugzar, Adam Lee Goldstein, Emad Tayem, Ori Galante, Milena Tocut

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Arie SorokskyIntensive Care Department, E. Wolfson Medical Center, Holon 58100, Israel.
Gingy Ronen BalmorIntensive Care Department, E. Wolfson Medical Center, Holon 58100, Israel.
Riziny NugzarFaculty of Medicine, Tel Aviv 69978, Israel.
Adam Lee GoldsteinFaculty of Medicine, Tel Aviv 69978, Israel.
Emad TayemIntensive Care Department, E. Wolfson Medical Center, Holon 58100, Israel.
Ori GalanteMedical Intensive Care Unit, Soroka University Medical Center, Be'er Sheva 84101, Israel.
Milena TocutFaculty of Medicine, Tel Aviv 69978, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLiberation from mechanical ventilation is a major objective in critically ill patients. Various criteria for extubation are used with different success rates. We developed a novel, simple bedside maneuver and index that involves measuring breath-hold duration and forced vital capacity (FVC). We named it the Respiratory Breath Hold Index (RBHI).

methodsWe enrolled 225 mechanically ventilated intensive care unit (ICU) patients who were candidates for extubation. At the end of a spontan eous breathing trial (SBT), and just prior to extubation, patients were asked to hold their breath and perform a stalked FVC maneuver. The ability to perform a breath-hold maneuver and its duration were recorded and compared with a standard SBT.

results171 patients (76%) were successfully extubated, while 54 patients (24%) failed extubation. A successful SBT alone did not predict extubation, as 80.1% of passed SBT and 81.5% of failed SBT patients were extubated successfully (

conclusionHigher RBHI, together with the ability to hold a breath just prior to extubation in mechanically ventilated patients, is more sensitive and specific, and may be superior to standard SBT in predicting a successful extubation.

Indexed as

extubationliberation from mechanical ventilationrespiratory breath hold indexspontaneous breathing trial

Identifiers

PMID41157214
PMCPMC12565644

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.