Evidence map›Paper›PMID 41157202›Full record

ArticleLife (Basel, Switzerland)2025

High-Dose Shilajit Enhances Xenograft-Mediated Bone Regeneration in a Rat Tibial Defect Model: An In Vivo Experimental Study.

Ridvan Guler, Ersin Ozden, Firat Asır, Belgin Gulsun

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ridvan GulerDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Dicle University, 21280 Diyarbakir, Turkey.ORCID 0000-0003-4750-9798
Ersin OzdenDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Firat University, 23119 Elazig, Turkey.ORCID 0000-0002-7160-8422
Firat AsırDepartment of Histology and Embryology, Faculty of Medicine, Dicle University, 21280 Diyarbakir, Turkey.ORCID 0000-0002-6384-9146
Belgin GulsunDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Dicle University, 21280 Diyarbakir, Turkey.ORCID 0000-0002-2456-7381

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shilajit, a natural herbo-mineral compound with potent antioxidant, anti-inflammatory, and osteogenic properties, has been traditionally used to promote tissue repair. However, limited experimental data exist on its localized application in bone regeneration. This study aimed to evaluate the combined effect of Shilajit and bovine-derived xenograft on bone healing in a rat tibial defect model. Twenty-eight male Sprague-Dawley rats were randomly assigned to four groups (

Indexed as

bone regenerationhistologyimmunohistochemistryoxidative stressShilajitTNF-αxenograft

Identifiers

PMID41157202
PMCPMC12565024

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.