ArticleLife (Basel, Switzerland)2025
The Association Between the Triglyceride-Glucose Index and the Risk of Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study.
Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Development and Validation of the Composite Renal-Inflammatory-Nutritional-Metabolic Index for Predicting 28-Day Mortality in Critically Ill Patients.Diagnostics (Basel, Switzerland) · 2026Article
- Explainable Lightweight AI for the Identification of Right-Sided Cardiac Dysfunction in a Saudi Arabian Diabetic Cohort.Journal of clinical medicine · 2026Article
- Impact of Patient Demographics and Cardiovascular Risk Factors on Percutaneous Coronary Intervention Outcomes.Cureus · 2026Article
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8 authors.
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Abstract
objectiveThis study aimed to evaluate the association between the triglyceride-glucose index (TGI) and the risk of cardiovascular disease in patients with type 2 diabetes mellitus.
methodsThis study included 1348 type 2 diabetic patients who attended the endocrinology clinic at Jordan University Hospital between March 2023 and September 2023. Medical records were reviewed to identify patients with documented cardiovascular disease, and the triglyceride-glucose index (TGI) was calculated for each patient.
resultsOur results showed that the TGI was higher among patients who developed any major adverse cardiovascular event (MACE), coronary artery disease (CAD), congestive heart failure (CHF), and/or myocardial infarction (MI) compared to those who did not (
conclusionThe TGI was shown to be associated with a significantly higher risk of a MACE, CAD, CHF, and MI in the whole population, along with stroke in males only. The TGI was more strongly associated with MACEs in patients younger than 60 years compared to older patients. In conclusion, the TGI was associated with cardiovascular outcomes in this diabetic cohort; however, its discriminative ability was modest (AUC 0.55-0.64). This indicates that the TGI alone is insufficient as a predictive tool and should be interpreted alongside established risk factors. Prospective studies are needed to clarify its incremental value in risk prediction.
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