Evidence map›Paper›PMID 41157070›Full record

ArticleMolecules (Basel, Switzerland)2025

Isolation and In Vitro Activity of Sesquiterpene Lactones from

Patricia Homobono Brito de Moura, Natalie Giovanna da Rocha Ximenes, Beatriz Bastos Santos, Carla Monteiro Leal, Larissa Esteves Carvalho Constant, Stephany da Silva Costa, Shaft Corrêa Pinto, Michelle Frazao Muzitano, Diego Allonso, Ludger A Wessjohann and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Patricia Homobono Brito de MouraLaboratory of Natural products and Biological Assays, Natural Products and Food Department, Pharmacy Faculty, Center of Health Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro 21941-902, RJ, Brazil.ORCID 0000-0001-6062-4788
Natalie Giovanna da Rocha XimenesLaboratory of Natural products and Biological Assays, Natural Products and Food Department, Pharmacy Faculty, Center of Health Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro 21941-902, RJ, Brazil.ORCID 0000-0002-0049-1132
Beatriz Bastos SantosLaboratory of Natural products and Biological Assays, Natural Products and Food Department, Pharmacy Faculty, Center of Health Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro 21941-902, RJ, Brazil.
Carla Monteiro LealLaboratory of Natural products and Biological Assays, Natural Products and Food Department, Pharmacy Faculty, Center of Health Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro 21941-902, RJ, Brazil.ORCID 0000-0003-2542-729X
Larissa Esteves Carvalho ConstantLaboratory of Biotechnology and Tissue Bioengineering, Institute of Biophysics Carlos Chagas Filho, Center of Health Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro 21941-902, RJ, Brazil.ORCID 0000-0003-4011-8532
Stephany da Silva CostaLaboratory of Biotechnology and Tissue Bioengineering, Institute of Biophysics Carlos Chagas Filho, Center of Health Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro 21941-902, RJ, Brazil.
Shaft Corrêa PintoLaboratory of Bioatives Products, Institute of Pharmaceutical Sciences, Federal University of Rio de Janeiro (UFRJ), Macaé 27933-378, RJ, Brazil.ORCID 0000-0003-1540-1440
Michelle Frazao MuzitanoLaboratory of Bioatives Products, Institute of Pharmaceutical Sciences, Federal University of Rio de Janeiro (UFRJ), Macaé 27933-378, RJ, Brazil.ORCID 0000-0003-0155-3240
Diego AllonsoDepartment of Pharmaceutical Biotechnology, Pharmacy Faculty, Center of Health Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro 21941-902, RJ, Brazil.ORCID 0000-0002-1410-480X
Ludger A WessjohannLeibniz Institute of Plant Biochemistry, Department of Bioorganic Chemistry, Weinberg 3, 06120 Halle, Germany.ORCID 0000-0003-2060-8235
Ivana Correa Ramos LealLaboratory of Natural products and Biological Assays, Natural Products and Food Department, Pharmacy Faculty, Center of Health Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro 21941-902, RJ, Brazil.ORCID 0000-0002-6917-9323

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Jurubatiba Sandbank National Park (PARNA Jurubatiba) is an ecological reserve characterized by harsh environmental conditions, including low rainfall, high sun exposure, and sandy soil. Among its native vegetation,

Indexed as

Coronavirus 3C ProteasesLactonesProtease InhibitorsSARS-CoV-2SesquiterpenesAntiviral AgentsCell Line, TumorCell SurvivalCOVID-19 Drug TreatmentHCT116 CellsHumansPC-3 CellsPlant Extracts3C-like proteinase, SARS-CoV-2Antiviral AgentsCoronavirus 3C ProteasesLactonesPlant ExtractsProtease InhibitorsSesquiterpenescentratherincytotoxicityEremanthus crotonoidesgoyazensolideSARS-CoV-2sesquiterpene lactones

Identifiers

PMID41157070
PMCPMC12566191

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.