Evidence map›Paper›PMID 41157068›Full record

ArticleMolecules (Basel, Switzerland)2025

Arylpiperazinyl-Benzocycloheptapyrrole-Carboxamides Endowed with Dual Anticancer and Antiviral Activities.

Gabriele Murineddu, Carlo Di Marzo, Paola Corona, Silvia Coinu, Erika Plicanti, Battistina Asproni, Sandra Piras, Giulia Freer, Antonio Carta

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gabriele MurinedduDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-2791-9178
Carlo Di MarzoCentro Retrovirus, Department of Translational Research, University of Pisa, 56127 Pisa, Italy.
Paola CoronaDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-9182-478X
Silvia CoinuDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0009-0001-4493-082X
Erika PlicantiCentro Retrovirus, Department of Translational Research, University of Pisa, 56127 Pisa, Italy.ORCID 0000-0002-5488-605X
Battistina AsproniDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-0988-1882
Sandra PirasDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.
Giulia FreerCentro Retrovirus, Department of Translational Research, University of Pisa, 56127 Pisa, Italy.ORCID 0000-0003-0787-2357
Antonio CartaDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.

Funding

Ministero dell'università e della ricerca PRIN 2022: 2022FRE3RH Dissecting the host cellular response to develop novel host-targeted approaches against RNA viruses. CUP I53D23000480006
6 · The paper itself

Abstract

In this work, we synthesized a small library of tricyclic compounds to assess whether they might have both anticancer and antiviral activity against three viruses that have recently caused epidemics. Concerning their anti-tumour activity, derivative

Indexed as

Antineoplastic AgentsAntiviral AgentsAnimalsCell Line, TumorDogsHumansInfluenza A virusMadin Darby Canine Kidney CellsSARS-CoV-2Zika VirusAntineoplastic AgentsAntiviral Agentsanticancerantiviralmicrowave irradiationtricyclic pyrroles

Identifiers

PMID41157068
PMCPMC12566046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.