Evidence map›Paper›PMID 41157061›Full record

ArticleMolecules (Basel, Switzerland)2025

Targeted Chemical Profiling and Dereplication of Australian Plants of the Family Haemodoraceae Using a Combined HPLC-MS and HRLC(ESI)-MS Approach.

Liam Thompson, Valerie Chow, Shan Chen, Priyanka Reddy, Robert Brkljača, Colin Rix, Joseph J Byrne, Aya C Taki, Robin B Gasser, Sylvia Urban

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Liam ThompsonMarine and Terrestrial Natural Product (MATNAP) Research Group, Department of Applied Chemistry and Environmental Science, School of Science, RMIT University, Melbourne, VIC 3001, Australia.
Valerie ChowMarine and Terrestrial Natural Product (MATNAP) Research Group, Department of Applied Chemistry and Environmental Science, School of Science, RMIT University, Melbourne, VIC 3001, Australia.
Shan ChenMarine and Terrestrial Natural Product (MATNAP) Research Group, Department of Applied Chemistry and Environmental Science, School of Science, RMIT University, Melbourne, VIC 3001, Australia.ORCID 0009-0009-0440-0195
Priyanka ReddySchool of Chemistry, Bio21 Institute of Molecular Science and Biotechnology, University of Melbourne, Parkville, VIC 3010, Australia.ORCID 0000-0002-1504-1126
Robert BrkljačaMonash Biomedical Imaging, Monash University, Clayton, VIC 3168, Australia.ORCID 0000-0001-6190-2276
Colin RixMarine and Terrestrial Natural Product (MATNAP) Research Group, Department of Applied Chemistry and Environmental Science, School of Science, RMIT University, Melbourne, VIC 3001, Australia.ORCID 0000-0001-7135-6598
Joseph J ByrneDepartment of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Science, The University of Melbourne, Parkville, VIC 3010, Australia.ORCID 0000-0001-5235-8408
Aya C TakiDepartment of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Science, The University of Melbourne, Parkville, VIC 3010, Australia.ORCID 0000-0003-3489-4367
Robin B GasserDepartment of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Science, The University of Melbourne, Parkville, VIC 3010, Australia.ORCID 0000-0002-4423-1690
Sylvia UrbanMarine and Terrestrial Natural Product (MATNAP) Research Group, Department of Applied Chemistry and Environmental Science, School of Science, RMIT University, Melbourne, VIC 3001, Australia.ORCID 0000-0002-2376-4260

Funding

Australian Research Council LP180101085Australian Research Council LP220200614
6 · The paper itself

Abstract

Australian plants of the family Haemodoraceae have been a reliable source of new secondary metabolites, particularly those of the 'phenylphenalenone' class, and related chromenes and xanthones. Some of these compounds demonstrate anti-microbial properties against both Gram-negative and Gram-positive bacteria. Chemical profiling of thirty individual ethanolic extracts from six separate species of Australian plants belonging to the family Haemodoraceae was conducted using an HPLC-MS approach reinforced by HRLC(ESI)-MS. Six of the extracts were further explored by employing HRLC(ESI)-MS and the compounds present were characterised and confirmed based on a comparison to the original data. All thirty extracts were assessed for biological activity against the parasitic nematode

Indexed as

Plant ExtractsAnimalsAustraliaChromatography, High Pressure LiquidHaemonchusLiquid Chromatography-Mass SpectrometryPhytochemicalsSpectrometry, Mass, Electrospray IonizationPhytochemicalsPlant Extractsanthelminticanti-microbialbioassayoxabenzochrysenonephenylbenzoisochromenonephenylphenalenone

Identifiers

PMID41157061
PMCPMC12566560

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.