Evidence map›Paper›PMID 41157023›Full record

ArticleMaterials (Basel, Switzerland)2025

Molecular Biocompatibility Assessment of PETG Aligners After Processing by Laser or Milling.

Katia Barbaro, Ginevra Ciurli, Ettore Candida, Francesca Silvestrini-Biavati, Valentina Lanteri, Paola Ghisellini, Cristina Rando, Roberto Eggenhöffner, Alessandro Ugolini

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Katia BarbaroIstituto Zooprofilattico Sperimentale del Lazio e della Toscana "M. Aleandri", 00178 Rome, Italy.ORCID 0000-0001-9830-996X
Ginevra CiurliIstituto Zooprofilattico Sperimentale del Lazio e della Toscana "M. Aleandri", 00178 Rome, Italy.
Ettore CandidaDepartment of Surgical Sciences and Integrated Diagnostics (DISC), Genova University, 16132 Genoa, Italy.
Francesca Silvestrini-BiavatiDepartment of Surgical Sciences and Integrated Diagnostics (DISC), Genova University, 16132 Genoa, Italy.ORCID 0000-0003-2899-8450
Valentina LanteriSurgical, Medical and Dental Department, University of Modena and Reggio Emilia, 41124 Modena, Italy.ORCID 0000-0003-2191-8673
Paola GhiselliniDepartment of Surgical Sciences and Integrated Diagnostics (DISC), Genova University, 16132 Genoa, Italy.ORCID 0000-0003-0505-0106
Cristina RandoDepartment of Surgical Sciences and Integrated Diagnostics (DISC), Genova University, 16132 Genoa, Italy.ORCID 0000-0003-2575-0257
Roberto EggenhöffnerDepartment of Surgical Sciences and Integrated Diagnostics (DISC), Genova University, 16132 Genoa, Italy.ORCID 0000-0001-7886-1829
Alessandro UgoliniDepartment of Surgical Sciences and Integrated Diagnostics (DISC), Genova University, 16132 Genoa, Italy.ORCID 0000-0002-2062-6014

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyethylene terephthalate glycol-modified (PETG) is a transparent, stable copolymer commonly used in biomedical devices such as surgical guides, clear aligners, and anatomical models. Its biocompatibility must be assessed not only for cytotoxicity, but also for subtle molecular and immunological responses, especially when in contact with mucosal or hormone-sensitive tissues. This study evaluated the biological safety of PETG processed via CNC milling and CO

Indexed as

endocrine disruptorsgene expression profilinginflammatory responselaser/milling cuttingPETG biocompatibility

Identifiers

PMID41157023
PMCPMC12566054

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.