Evidence map›Paper›PMID 41156864›Full record

ArticleMicroorganisms2025

Urobiome Signatures of Recurrent Urinary Tract Infections in Adolescent Pregnancy: A Longitudinal Study.

Carlos Daniel Mora-Vargas, Orly Grobeisen-Duque, Oscar Villavicencio-Carrisoza, Diana Angélica Aguilar-Ayala, Orlando Castellanos-Diaz, Maria Guadalupe Martinez-Salazar, Alejandro Rosas-Balan, Veronica Flores-Rueda, Moises Leon-Juarez, Mario Guzman-Huerta and 5 more

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Carlos Daniel Mora-VargasDepartamento de Inmunobioquímica, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Ciudad de México 11000, Mexico.
Orly Grobeisen-DuqueDepartamento de Inmunobioquímica, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Ciudad de México 11000, Mexico.ORCID 0000-0001-6541-5934
Oscar Villavicencio-CarrisozaDepartamento de Inmunobioquímica, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Ciudad de México 11000, Mexico.ORCID 0000-0002-7091-8840
Diana Angélica Aguilar-AyalaDepartamento de Inmunobioquímica, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Ciudad de México 11000, Mexico.ORCID 0000-0001-5280-4260
Orlando Castellanos-DiazDivisión de Ciencias Básicas e Ingeniería, Departamento de Ingeniería Eléctrica, Universidad Autónoma Metropolitana, Unidad Iztapalapa, Ciudad de México 09310, Mexico.ORCID 0009-0000-7867-8688
Maria Guadalupe Martinez-SalazarDepartamento de Inmunobioquímica, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Ciudad de México 11000, Mexico.
Alejandro Rosas-BalanCoordinación de Medicina de la Adolescente, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Ciudad de México 11000, Mexico.
Veronica Flores-RuedaCoordinación de Medicina de la Adolescente, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Ciudad de México 11000, Mexico.
Moises Leon-JuarezDepartamento de Inmunobioquímica, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Ciudad de México 11000, Mexico.ORCID 0000-0002-5726-5953
Mario Guzman-HuertaDepartamento de Medicina Traslacional, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Ciudad de México 11000, Mexico.
Lisbeth Camargo-MarinDepartamento de Medicina Traslacional, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Ciudad de México 11000, Mexico.
Maria Isabel Villegas-MotaSecretaría de Salud del Estado de Quintana Roo, Chetumal 7700, Mexico.ORCID 0000-0001-6678-1282
Veronica Zaga-ClavellinaDepartamento de Inmunobioquímica, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Ciudad de México 11000, Mexico.ORCID 0000-0002-3365-2932
Ma Guadalupe Aguilera-ArreolaEscuela Nacional de Ciencias Biológicas del Instituto Politécnico Nacional, Ciudad de México 11350, Mexico.
Addy Cecilia Helguera-RepettoDepartamento de Inmunobioquímica, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Ciudad de México 11000, Mexico.ORCID 0000-0001-6715-9671

Funding

Secretaría de Ciencia, Humanidades, Tecnología e Innovación FOSISS FONDO SECTORIAL DE INVESTIGACIÓN EN SALUD Y SEGURIDAD SOCIAL 290038
6 · The paper itself

Abstract

Adolescent pregnancy is a significant public health concern, with maternal and fetal risks compounded by pregnancy-related anatomical, hormonal, and urinary changes that predispose to urinary tract infections (UTIs). Alterations in the urinary microbiome may further influence infection susceptibility, yet little is known about its role during adolescent pregnancy. This study analyzed the urinary microbiome of adolescent pregnant patients and its association with UTI and recurrent UTI (rUTI) across gestation. Healthy adolescents were enrolled in the first trimester and followed through subsequent trimesters, with urine samples collected at each visit for microbiological diagnosis. Patients were classified as healthy (34 samples), single UTI (22 samples), or rUTI (31 samples), and oxford-nanopore 16S rRNA sequencing was used to assess taxonomic composition, microbial diversity, and operational taxonomic units. Distinct trimester-specific patterns were observed, with

Indexed as

adolescent pregnancyE. coliLatin Americamicrobiomerecurrent UTIUPECurinary tract infectionurobiomeUTI

Identifiers

PMID41156864
PMCPMC12566430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.