Sodium Butyrate Supplementation in Whole Milk Modulates the Gastrointestinal Microbiota Without Altering the Resistome and Virulome in Preweaned Calves.

Liwen Xing, Song Niu, Donglin Wu, Zhanghe Zhang, Ming Xu

Abstract read

In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Liwen XingCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.

Song NiuCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.

Donglin WuCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.

Zhanghe ZhangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.

Ming XuCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.

Funding

Natural Science Foundation of Inner Mongolia Autonomous Region 2023LHMS03048Universitiy Basic Research Fund Project of Inner Mongolia Autonomous Region BR221506

6 · The paper itself

Abstract

This study investigated the effects of supplementing whole milk (WM) with sodium butyrate (SB) on the gastrointestinal microbiota of preweaned calves. Twelve newborn Holstein calves (4 days old, 39.21 ± 1.45 kg) were randomly assigned into one of two dietary treatments: (1) WM without SB (CON) and (2) WM supplemented with SB (8.8 g/d; SB). At 74 days of age, all calves were slaughtered to collect ruminal and cecal digesta. Metagenomic analysis was used to characterize the microbial composition, virulence factor genes (VFGs), and antibiotic resistance genes (ARGs). SB supplementation altered the ruminal microbial composition and increased the abundance of beneficial bacteria, including

Indexed as

calf feedingcecum microbiotametagenomic sequencingrumen microbiotasodium butyrate

Identifiers

PMID41156833

DOI10.3390/microorganisms13102375

PMCPMC12566572

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.