Evidence map›Paper›PMID 41156831›Full record

ArticleMicroorganisms2025

Multi-Omics Insights into Gingivitis from a Clinical Trial: Understanding the Role of Bacterial and Host Factors.

Niranjan Ramji, Ping Hu, Alejandra Muñoz Bodnar, Camila Pereira Braga, John Snowball, Dionne Swift, Hao Ye, Sancai Xie, Rachel Trenner, Malgorzata Klukowska and 2 more

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Niranjan RamjiOral Care, Global R&D, The Procter & Gamble Company, Mason, OH 45040, USA.
Ping HuDiscovery & Innovation Platforms, Corporate Function R&D, The Procter & Gamble Company, Mason, OH 45040, USA.ORCID 0000-0003-1100-9361
Alejandra Muñoz BodnarOral Care, Global R&D, The Procter & Gamble Company, Mason, OH 45040, USA.
Camila Pereira BragaDiscovery & Innovation Platforms, Corporate Function R&D, The Procter & Gamble Company, Mason, OH 45040, USA.
John SnowballDiscovery & Innovation Platforms, Corporate Function R&D, The Procter & Gamble Company, Mason, OH 45040, USA.
Dionne SwiftDiscovery & Innovation Platforms, Corporate Function R&D, The Procter & Gamble Company, Mason, OH 45040, USA.
Hao YeOral Care, Global R&D, The Procter & Gamble Company, Mason, OH 45040, USA.
Sancai XieDiscovery & Innovation Platforms, Corporate Function R&D, The Procter & Gamble Company, Mason, OH 45040, USA.
Rachel TrennerOral Care, Global R&D, The Procter & Gamble Company, Mason, OH 45040, USA.
Malgorzata KlukowskaOral Care, Global R&D, The Procter & Gamble Company, Mason, OH 45040, USA.
Eva SchneidermanOral Care, Global R&D, The Procter & Gamble Company, Mason, OH 45040, USA.
Aaron R BiesbrockOral Care, Global R&D, The Procter & Gamble Company, Mason, OH 45040, USA.

Funding

Procter & Gamble (United States) n/a
6 · The paper itself

Abstract

Poor oral health is a neglected epidemic, potentially contributing to systemic health issues. We employed a multi-omics approach to investigate the biological changes associated with gingivitis and the effects of stannous fluoride (SnF

Indexed as

microbiomeperiodontal diseaseproteomicssingle cellstannous fluoridesystematic effect

Identifiers

PMID41156831
PMCPMC12566121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.