ArticleMicroorganisms2025
Long-Term Sewage Survey of SARS-CoV-2, Influenza A and Respiratory Syncytial Virus (RSV), and Correlation to Human Cases in a City with One Million Inhabitants.
Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Detection of Respiratory Viruses in Wastewater Samples Using Commercial Multiplex PCR Assays.Viruses · 2026Article
- Toward a quality-managed operational architecture for wastewater surveillance of zoonotic and emerging pathogens.Applied and environmental microbiology · 2026Review
- Wastewater-Based Surveillance of Respiratory Viruses in the SARS-CoV-2 Post-Pandemic Period in Mexico.Viruses · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wastewater-based epidemiology is a robust, scalable, cost-effective, and high-performing tool to monitor and predict SARS-CoV-2 trends. We aimed to investigate whether this approach could be applied to influenza A/B viruses and respiratory syncytial virus (RSV) in Marseille, southern France. Wastewater concentrations of SARS-CoV-2, influenza A/B viruses, and RSV in Marseille were monitored by qPCR between January 2021 and October 2024. These concentrations were compared with the diagnosis numbers for the three viruses collected at public hospitals in Marseille, using cross-correlation analyses. The Granger causality test was used to determine whether wastewater concentrations can predict the number of clinical cases. SARS-CoV-2 and influenza virus concentrations in wastewater preceded the rise in the incidence of patient diagnoses by a lag of five days and nine/ten days, respectively. In contrast, for RSV, the rise in incidence of clinical cases preceded that of wastewater concentrations. We conclude that wastewater-based epidemiology is a powerful tool to monitor the level of circulation of these viruses independently of tests carried out on people. It enables earlier alerts than monitoring patients for SARS-CoV-2 and influenza symptoms. However, for RSV, it does not provide an early warning, and clinical data-based surveillance appears to be more suitable.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.