Evidence map›Paper›PMID 41156719›Full record

ArticleMicroorganisms2025

Microbiological Safety of Donor Human Milk: Comparing Culture-Based Methods for Enterobacterales Detection.

Lena Dawczynski, Nora Helke Leder, Sabine Trommer, Frank Kipp, Claudia Stein

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lena DawczynskiInstitute for Infectious Diseases and Infection Control, Jena University Hospital, 07747 Jena, Germany.
Nora Helke LederInstitute for Infectious Diseases and Infection Control, Jena University Hospital, 07747 Jena, Germany.
Sabine TrommerInstitute for Infectious Diseases and Infection Control, Jena University Hospital, 07747 Jena, Germany.
Frank KippInstitute for Infectious Diseases and Infection Control, Jena University Hospital, 07747 Jena, Germany.
Claudia SteinInstitute for Infectious Diseases and Infection Control, Jena University Hospital, 07747 Jena, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In neonatal care, donor human milk (DHM) is used when maternal milk is unavailable or insufficient. In several countries, including Germany, raw (i.e., unpasteurised) DHM is occasionally administered under specific clinical conditions. However, the lack of standardised, evidence-based microbiological testing protocols raises concerns about the reliability of safety assessments for this high-risk patient group. The objective of this study was to assess the performance of four culture-based microbiological methods for detecting Enterobacterales in donor human milk, using both spiked samples and raw milk. We compared the detection limits of four culture-based microbiological methods, with and without enrichment, using spiked DHM samples and 93 raw DHM samples from a single donor (limited generalisation). Artificially inoculated samples contained defined concentrations of

Indexed as

culture-based methodsdiagnostic sensitivitydonor human milkEnterobacteralesmicrobiological screeningneonatal careneonatal feedingunpasteurised milk

Identifiers

PMID41156719
PMCPMC12566355

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.