Evidence map›Paper›PMID 41156693›Full record

ArticleMicroorganisms2025

Cyclic di-GMP Modulation of Quorum Sensing and Its Impact on Type VI Secretion System Function in

Juan Aranda-Pérez, María Del Carmen Sánchez-Aguilar, Ana María Cutiño-Gobea, Francisco Pérez-Montaño, Carlos Medina

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Juan Aranda-PérezDepartamento de Microbiología, Facultad de Biología, Universidad de Sevilla, Avda. Reina Mercedes 6, CP41012 Sevilla, Spain.
María Del Carmen Sánchez-AguilarDepartamento de Microbiología, Facultad de Biología, Universidad de Sevilla, Avda. Reina Mercedes 6, CP41012 Sevilla, Spain.ORCID 0009-0001-6637-1459
Ana María Cutiño-GobeaDepartamento de Microbiología, Facultad de Biología, Universidad de Sevilla, Avda. Reina Mercedes 6, CP41012 Sevilla, Spain.
Francisco Pérez-MontañoDepartamento de Microbiología, Facultad de Biología, Universidad de Sevilla, Avda. Reina Mercedes 6, CP41012 Sevilla, Spain.ORCID 0000-0002-6272-2063
Carlos MedinaDepartamento de Microbiología, Facultad de Biología, Universidad de Sevilla, Avda. Reina Mercedes 6, CP41012 Sevilla, Spain.ORCID 0000-0003-0069-7330

Funding

FEDER program PPIT2024-31787Spanish Minister of Science, Innovation and Universities (MICIU) PID2020-118279RA-I00
6 · The paper itself

Abstract

Effective rhizobium-legume symbiosis depends on multiple molecular signaling pathways, integrating not only classical nodulation factors and surface polysaccharides but also diverse protein secretion systems. Among them, the Type VI Secretion System (T6SS) has emerged as a key player, due to its dual roles in interbacterial competition and interactions with eukaryotic hosts, though its contribution to symbiosis remains unclear. Key regulatory messengers, including the main autoinducer of the quorum sensing (QS) systems, the

Indexed as

biofilmscyclic di-GMP (c-di-GMP)legumesN-acyl homoserine lactones (AHLs)nodulationquorum sensing (QS)Sinorhizobium frediisymbiosisType VI Secretion System (T6SS)

Identifiers

PMID41156693
PMCPMC12565851

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.