Evidence map›Paper›PMID 41156665›Full record

ReviewPathogens (Basel, Switzerland)2025

Plasmid Genomic Dynamics and One Health: Drivers of Antibiotic Resistance and Pathogenicity.

Célia P F Domingues, João S Rebelo, Francisco Dionisio, Teresa Nogueira

Abstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Célia P F DominguescE3c-Centre for Ecology, Evolution and Environmental Changes & Change, Global Change and Sustainability Institute, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisboa, Portugal.ORCID 0000-0003-2970-010X
João S RebelocE3c-Centre for Ecology, Evolution and Environmental Changes & Change, Global Change and Sustainability Institute, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisboa, Portugal.ORCID 0000-0002-8662-7378
Francisco DionisiocE3c-Centre for Ecology, Evolution and Environmental Changes & Change, Global Change and Sustainability Institute, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisboa, Portugal.ORCID 0000-0002-3653-1511
Teresa NogueiracE3c-Centre for Ecology, Evolution and Environmental Changes & Change, Global Change and Sustainability Institute, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisboa, Portugal.ORCID 0000-0002-0059-5177

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Seen through a One Health perspective, plasmids act as global links, connecting human, animal, and environmental microbiomes while broadening the ecological scope of resistance and virulence. By combining knowledge about plasmid classification, mobility, resistance, virulence, and data sources, this review emphasizes their key role as drivers of bacterial evolution and worldwide health risks. Recognizing plasmids as connectors across microbiomes highlights both the urgency and opportunity to address plasmid-mediated resistance with integrated strategies. Current plasmid databases, such as NCBI RefSeq, PLSDB, IMG/PR, and PlasmidScope, have already greatly advanced our understanding of these connections, and they are likely to profoundly alter how we see plasmid biology and One Health relationships.

Indexed as

BacteriaDrug Resistance, BacterialDrug Resistance, MicrobialGenome, BacterialOne HealthPlasmidsAnimalsGenomicsHumansMicrobiotaVirulenceantibiotic resistance genesbacterial evolutiongenomicshorizontal gene transfermultidrug resistanceone healthplasmid classificationplasmidsvirulence genes

Identifiers

PMID41156665
PMCPMC12567507

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.