Evidence map›Paper›PMID 41156608›Full record

ArticlePathogens (Basel, Switzerland)2025

Post-COVID-19 Epidemiology of Viral Infections in Adults Hospitalized with Acute Respiratory Syndromes in Palermo, South of Italy.

Mariangela Pizzo, Floriana Bonura, Federica Cacioppo, Emilia Palazzotto, Chiara Filizzolo, Sharon Russo, Daniela Pistoia, Giuseppina Capra, Donatella Ferraro, Giovanni M Giammanco and 1 more

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Observational
  3. Community-AcquiredPathogens (Basel, Switzerland) · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mariangela PizzoDepartment of Health Promotion, Mother and Child Care, Internal Medicine, Medical Specialties (PROMISE), University of Palermo, 90127 Palermo, Italy.ORCID 0000-0001-7790-2828
Floriana BonuraDepartment of Health Promotion, Mother and Child Care, Internal Medicine, Medical Specialties (PROMISE), University of Palermo, 90127 Palermo, Italy.ORCID 0000-0002-9293-5924
Federica CacioppoDepartment of Health Promotion, Mother and Child Care, Internal Medicine, Medical Specialties (PROMISE), University of Palermo, 90127 Palermo, Italy.ORCID 0000-0001-7072-5718
Emilia PalazzottoDepartment of Health Promotion, Mother and Child Care, Internal Medicine, Medical Specialties (PROMISE), University of Palermo, 90127 Palermo, Italy.
Chiara FilizzoloDepartment of Health Promotion, Mother and Child Care, Internal Medicine, Medical Specialties (PROMISE), University of Palermo, 90127 Palermo, Italy.ORCID 0009-0000-5876-0406
Sharon RussoMicrobiology and Virology Unit, University Hospital "Paolo Giaccone", 90127 Palermo, Italy.
Daniela PistoiaMicrobiology and Virology Unit, University Hospital "Paolo Giaccone", 90127 Palermo, Italy.
Giuseppina CapraDepartment of Health Promotion, Mother and Child Care, Internal Medicine, Medical Specialties (PROMISE), University of Palermo, 90127 Palermo, Italy.ORCID 0000-0002-1407-7282
Donatella FerraroDepartment of Health Promotion, Mother and Child Care, Internal Medicine, Medical Specialties (PROMISE), University of Palermo, 90127 Palermo, Italy.
Giovanni M GiammancoDepartment of Health Promotion, Mother and Child Care, Internal Medicine, Medical Specialties (PROMISE), University of Palermo, 90127 Palermo, Italy.ORCID 0000-0002-7874-6289
Simona De GraziaDepartment of Health Promotion, Mother and Child Care, Internal Medicine, Medical Specialties (PROMISE), University of Palermo, 90127 Palermo, Italy.ORCID 0000-0001-7748-0880

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the epidemiology and seasonal patterns of respiratory viruses in adults hospitalized with acute respiratory tract infections during two consecutive post-COVID-19 pandemic seasons. A retrospective study was conducted at the University Hospital "P. Giaccone", Palermo, from September 2022 to September 2024. Multiplex molecular assays were used to detect the ten respiratory viruses most relevant from an epidemiological perspective in respiratory samples (n = 1110) of 1081 patients. A respiratory viral infection was identified in 29.6% of patients. The highest viral infection rate was observed in the 31-50 age group. Human rhinovirus/enterovirus (HRV/EV) was the most frequently detected (40%), followed by influenza A virus (IAV; 18.4%) and human coronaviruses (HuCoVs; 12.8%). Viral co-infections were identified in 10.9% of positive cases, with HRV/EV, adenovirus (ADV), and parainfluenza virus (PIV) being most frequently involved. Influenza and respiratory syncytial viruses (RSVs) showed a winter seasonality, while diverse circulation patterns were revealed for the other viruses. This study demonstrated a sustained circulation of respiratory viruses in adults hospitalized with severe respiratory symptoms, with HRV/EV accounting for most of them. Syndromic multiplex molecular testing, although limited to the detection of a small fraction of epidemiologically relevant known viruses, has proven to be a valuable tool, not only for diagnostic purposes but also for acquiring genotyping data and implementing epidemiological information from sentinel surveillance systems.

Indexed as

COVID-19Respiratory Tract InfectionsVirus DiseasesAdolescentAdultAgedAged, 80 and overCoinfectionFemaleHospitalizationHumansItalyMaleMiddle AgedRetrospective StudiesSARS-CoV-2COVID-19 pandemicItalyrespiratory tract infectionsrespiratory virusesseasonalitysyndromic assays

Identifiers

PMID41156608
PMCPMC12567287

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.