Evidence map›Paper›PMID 41156586›Full record

ArticlePathogens (Basel, Switzerland)2025

Surveillance of Acute Flaccid Paralysis (AFP) in Greece: 2008-2024.

Stavroula Labropoulou, Theano Georgakopoulou, Vahid Baniasadi, Giota Mpizta, Stella Vorre, Maria Theodoridou, Mary Emmanouil, Emmanouil Angelakis

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Stavroula LabropoulouNational Poliovirus/Enterovirus Reference Laboratory, Hellenic Pasteur Institute, 11521 Athens, Greece.
Theano GeorgakopoulouDepartment for Vaccine-Preventable Diseases & Congenital Diseases, National Public Health Organization, 15123 Athens, Greece.
Vahid BaniasadiDiagnostic Department and Public Health Laboratories, Hellenic Pasteur Institute, 11521 Athens, Greece.
Giota MpiztaDiagnostic Department and Public Health Laboratories, Hellenic Pasteur Institute, 11521 Athens, Greece.
Stella VorreDepartment for Vaccine-Preventable Diseases & Congenital Diseases, National Public Health Organization, 15123 Athens, Greece.
Maria Theodoridou1st Department of Paediatrics, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Mary EmmanouilNational Poliovirus/Enterovirus Reference Laboratory, Hellenic Pasteur Institute, 11521 Athens, Greece.ORCID 0000-0002-8970-3647
Emmanouil AngelakisNational Poliovirus/Enterovirus Reference Laboratory, Hellenic Pasteur Institute, 11521 Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As part of the WHO's Global Polio Eradication Initiative, acute flaccid paralysis (AFP) surveillance in children under 15 years old is crucial for monitoring the emergence of polioviruses and tracking Non-Polio Enteroviruses (NPEVs). This study outlines the past 17 years of AFP surveillance in Greece from 2008 to 2024, during which a total of 256 AFP cases were recorded. Stool samples from these cases were analyzed using virus isolation in cell cultures (RD/L20B) and sequencing of NPEV-positive samples. The Attica region reported the highest number of cases with 81 (31%), followed by Central Macedonia and Crete, each with 29 cases (11%). The overall analysis of fecal specimens identified the etiological agent in 18 (7%) specimens, with 13 (4.7%) classified as NPEVs, 4 (1.5%) as adenoviruses, and 1 (0.4%) as a parechovirus. Coxsackievirus A, Coxsackievirus B, and various Echoviruses were the most frequently detected NPEV types. Notably, more than half of these positive specimens (10/18) were from the Attica region, which has the highest population density. These findings highlight the ongoing relevance of AFP surveillance in polio-free settings for broader pathogen monitoring and public health preparedness. Continued vigilance and investment in AFP surveillance are critical to sustaining Greece's polio-free status and detecting emerging viral threats.

Indexed as

Central Nervous System Viral DiseasesEnterovirus InfectionsEpidemiological MonitoringParalysisAdolescentChildChild, PreschoolEnterovirusFecesFemaleGreeceHumansInfantMaleMyelitisNeuromuscular Diseasesacute flaccid paralysisenterovirusGreecepolio

Identifiers

PMID41156586
PMCPMC12567247

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.