ArticlePathogens (Basel, Switzerland)2025
The Differential Early Responses of Human Leukocytes to Influenza Virus and Respiratory Syncytial Virus.
Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Programmed cell death in human respiratory syncytial virus infection.Frontiers in cellular and infection microbiology · 2025Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The current studies examined very early events associated with activation and initiation of a human immune response after sham exposure or exposure to influenza virus (IAV) versus respiratory syncytial virus (RSV), focusing on the function of a critical accessory cell for lymphocyte responses. Calcium mobilization by monocytes/macrophages was rapid and marked in response to exposure to IAV but was muted in response to RSV. Monocytes/macrophages exposed to IAV showed markedly enhanced expression of Cox-2 mRNA measured soon after exposure, whereas exposure to RSV resulted in reduced expression (relative to control cells). In contrast, expression of the constitutively expressed 2.8 kb Cox-1 mRNA was relatively constant. The 72/74 kDa/pl 7.5 protein doublet (product of the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.