Loss of Type 1 Pili and Flagella in Uropathogenic

Abstract read

In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Immuno-phage synergy driven by fitness costs: turning bacterial phage resistance into therapeutic gain through evolutionary traps.Frontiers in immunology · 2026
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

William R SchwanDepartment of Microbiology, University of Wisconsin-La Crosse, La Crosse, WI 54601, USA.ORCID 0000-0003-3076-1815

Funding

OmpR and acid regulation of Escherichia coli fim genesR15AI065432 · NIAID · UNIVERSITY OF WISCONSIN LA CROSSE · PI SCHWAN, WILLIAM R · 2007 to 2007

$185k

NIAID NIH HHS R15 AI065432NIH HHS 1R15AI065432-06

6 · The paper itself

Abstract

backgroundUropathogenic

methodsIn this study, Δ

resultsA Δ

conclusionThe data show that the loss of both type 1 pili and flagella expression on the UPEC cells reduces phagocytosis of the bacteria by human and murine monocytes. Although type 1 pili and flagella are important for establishing a UTI and ascension into the kidneys, the loss of these proteinaceous structures may allow the UPEC cells to evade the innate immune defenses in certain environments within the human body.

Indexed as

Escherichia coli InfectionsFimbriae, BacterialFlagellaMonocytesPhagocytosisUropathogenic Escherichia coliAnimalsCell LineEscherichia coli ProteinsHumansMiceUrinary Tract InfectionsEscherichia coli Proteinsflagellatype 1 fimbriaetype 1 piliuropathogenic Escherichia coli

Identifiers

PMID41156579

DOI10.3390/pathogens14100968

PMCPMC12567150

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.