Numerical and Experimental Analysis of Microparticle Focusing and Separation in Split-Recombination Microchannel.

Shuang Chen, Jiajia Sun, Zongqian Shi, Lijie Sun, Junxiong Guo

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Article in Micromachines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Shuang ChenSchool of Electronic Information and Electrical Engineering, Chengdu University, Chengdu 610106, China.

Jiajia SunState Key Laboratory of Electrical Insulation and Power Equipment, Xi'an Jiaotong University, Xi'an 710049, China.

Zongqian ShiState Key Laboratory of Electrical Insulation and Power Equipment, Xi'an Jiaotong University, Xi'an 710049, China.

Lijie SunSchool of Electronic Information and Electrical Engineering, Chengdu University, Chengdu 610106, China.

Junxiong GuoSchool of Electronic Information and Electrical Engineering, Chengdu University, Chengdu 610106, China.ORCID 0000-0002-0071-1086

Funding

National Natural Science Foundation of China 52307015

6 · The paper itself

Abstract

Inertial microfluidics has obtained attention for its good performance in microparticle manipulation. It has the advantages of simplicity, high throughput, and a lack of external fields. In this paper, a simple microfluidic device is described, which contains several split and recombination structures. The design takes advantage of microparticle migration based on inertial lift and the Dean drag force. Two forces drive microparticles to move laterally and arrive at equilibrium positions in a split-recombination microchannel. Based on the numerical and experimental analysis, the trajectories of microparticles are described, and microparticles are focused and form two narrow streams. In addition, the focusing of microparticles is enhanced significantly with the increase in angle. Finally, two sizes of microparticles are separated in experiments. The simple device and high throughput offered by this passive microfluidic approach make it attractive in biomedical and environmental applications.

Indexed as

Dean drag forcefocusing and separationinertial lift forcemicrofluidicsmicroparticle

Identifiers

PMID41156392

DOI10.3390/mi16101145

PMCPMC12566562

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.