Taguchi-Based Optimization of FDM Parameters for Sub-150 µm Microchannels: Comparative Study of PETG and TPU.

The fabrication of microfluidic components using low-cost Fused Deposition Modeling (FDM) presents an attractive alternative to conventional manufacturing methods, yet achieving microscale dimensional accuracy remains a significant challenge. This study investigates the influence of five key FDM parameters (nozzle temperature, bed temperature, printing speed, flow rate, and infill overlap) on the dimensional accuracy of microchannels printed with PETG and TPU filaments. A Taguchi L27 orthogonal array was employed to systematically evaluate the effects of these parameters on width and depth deviations across sub-millimeter microchannel geometries. Results show that for PETG, optimal dimensional fidelity was achieved at 240 °C nozzle temperature, 70 °C bed temperature, 30 mm/s speed, 100% flow rate, and 15% overlap, enabling reliable channel widths down to 100 µm. TPU exhibited greater variability due to its elasticity, with optimal settings found at 220 °C, 60 °C bed temperature, 30 mm/s, 100% flow rate, and 25% overlap. Signal-to-noise ratio and ANOVA analyses revealed flow rate and printing speed as dominant factors for both materials. The findings provide a reproducible optimization framework for microscale FDM fabrication and highlight material-specific process sensitivities critical to functional microfluidic device performance.