ArticlePharmaceutics2025
Design, Synthesis, In Vitro and In Silico Biological Evaluation of New Pyridine-2,5-Dicarboxylates Esters Bearing Natural Source Fragments as Anti-Trypanosomatid Agents.
Luis M Sánchez-Palestino, Adriana Moreno-Rodríguez, Diana V Navarrete-Carriola, Marlet Martínez-Archundia, Marhian López-Vargas, Liliana Argueta-Figueroa, Lenci K Vázquez-Jiménez, Alma D Paz-González, Eyra Ortiz-Pérez, Michael P Doyle and 1 more
Abstract read
In one paragraphArticle in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
11 authors.
Luis M Sánchez-PalestinoLaboratorio de Biotecnología Farmacéutica, Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Reynosa 88710, Mexico.
Adriana Moreno-RodríguezLaboratorio de Estudios Epidemiológicos, Clínicos, Diseños Experimentales e Investigación, Facultad de Ciencias Químicas, Universidad Autónoma "Benito Juárez" de Oaxaca, Avenida Universidad S/N, Ex Hacienda Cinco Señores, Oaxaca 68120, Mexico.
Diana V Navarrete-CarriolaLaboratorio de Biotecnología Farmacéutica, Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Reynosa 88710, Mexico.
Marlet Martínez-ArchundiaLaboratory for the Design and Development of New Drugs and Biotechnological Innovation, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, Ciudad de México 11340, Mexico.ORCID 0000-0002-6140-8953 Marhian López-VargasLaboratorio de Estudios Epidemiológicos, Clínicos, Diseños Experimentales e Investigación, Facultad de Ciencias Químicas, Universidad Autónoma "Benito Juárez" de Oaxaca, Avenida Universidad S/N, Ex Hacienda Cinco Señores, Oaxaca 68120, Mexico.ORCID 0009-0007-3976-2327 Liliana Argueta-FigueroaSECIHTI-Tecnológico Nacional de México, Instituto Tecnológico de Toluca, Metepec 52149, Mexico.ORCID 0000-0002-1044-6757 Lenci K Vázquez-JiménezLaboratorio de Biotecnología Farmacéutica, Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Reynosa 88710, Mexico.ORCID 0000-0002-9327-9658 Alma D Paz-GonzálezLaboratorio de Biotecnología Farmacéutica, Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Reynosa 88710, Mexico.
Eyra Ortiz-PérezLaboratorio de Biotecnología Farmacéutica, Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Reynosa 88710, Mexico.ORCID 0000-0003-3800-0228 Michael P DoyleDepartment of Chemistry, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA.ORCID 0000-0003-1386-3780 Gildardo RiveraLaboratorio de Biotecnología Farmacéutica, Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Reynosa 88710, Mexico.ORCID 0000-0001-9842-4167 Funding
Secretaria de Ciencia, Humanidades, Tecnología e Innovacion (SECIHTI) CF-2023-I-1738 and CF-2023-I-1969
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
1,2,3-triazine 1-oxideADMET propertiesantiprotozoal agentsnatural productspyridine hybrid derivatives
Identifiers
PMID41155908
PMCPMC12566703
What OpenQuestion holds
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