Evidence map›Paper›PMID 41155891›Full record

ArticlePharmaceutics2025

mRNA-Based Combination Therapy for Inflammation-Driven Osteoarthritis Induced by Monosodium Iodoacetate.

Yuki Terai, Erica Yada, Hideyuki Nakanishi, Keiji Itaka

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuki TeraiClinical Biotechnology Team, Center for Infectious Disease Education and Research (CiDER), The University of Osaka, Suita 565-0871, Japan.ORCID 0000-0002-0391-5367
Erica YadaLaboratory of Biomaterials and Bioengineering, Institute of Integrated Research, Institute of Science Tokyo, Tokyo 101-0062, Japan.
Hideyuki NakanishiClinical Biotechnology Team, Center for Infectious Disease Education and Research (CiDER), The University of Osaka, Suita 565-0871, Japan.ORCID 0000-0003-1159-3676
Keiji ItakaClinical Biotechnology Team, Center for Infectious Disease Education and Research (CiDER), The University of Osaka, Suita 565-0871, Japan.ORCID 0000-0001-5132-5356

Funding

Axcelead NoneJapan Agency for Medical Research and Development 20pc0101062h0001Japan Agency for Medical Research and Development 25ak0101173s0205Japan Agency for Medical Research and Development JP223fa627002Japan Science and Technology Agency JPMJPF2202Japan Science and Technology Agency JPMJSP2180Japan Society for the Promotion of Science JP23H03737
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

chondroprotectioninterleukin-1 receptor antagonist (IL-1Ra)intra-articular deliverymRNA therapeuticsosteoarthritispolyplex nanomicellerunt-related transcription factor 1 (RUNX1)

Identifiers

PMID41155891
PMCPMC12567188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.