Evidence map›Paper›PMID 41155878›Full record

ArticlePharmaceutics2025

LMT2368 (1-(4-Chlorophenyl)-3-(3-fluoro-5-(trifluoromethyl)phenyl)urea) Negatively Regulates Inflammation by Inhibiting NLRP3 Inflammasome Activation.

Thai Uy Nguyen, Su Jeong Kwon, Sunghoon Hurh, Ashok Kale, Jae Min Cho, Hossam Nada, Chang Seong Kim, Peela Induvadana, Beom Jin Park, Kyeong Lee and 2 more

Abstract read
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Thai Uy NguyenDepartment of Biomedical Science, College of Medicine, Korea University, Seoul 73 Goryeodae-ro, Seongbuk-gu, Seoul 02841, Republic of Korea.ORCID 0000-0002-4908-1185
Su Jeong KwonBrain Korea 21 Fostering Outstanding Universities for Research, Team and Integrated Research Institute for Drug Development, College of Pharmacy, Dongguk University, Seoul 02841, Republic of Korea.
Sunghoon HurhDepartment of Biomedical Science, College of Medicine, Korea University, Seoul 73 Goryeodae-ro, Seongbuk-gu, Seoul 02841, Republic of Korea.
Ashok KaleBrain Korea 21 Fostering Outstanding Universities for Research, Team and Integrated Research Institute for Drug Development, College of Pharmacy, Dongguk University, Seoul 02841, Republic of Korea.
Jae Min ChoBrain Korea 21 Fostering Outstanding Universities for Research, Team and Integrated Research Institute for Drug Development, College of Pharmacy, Dongguk University, Seoul 02841, Republic of Korea.ORCID 0009-0009-8793-3076
Hossam NadaBrain Korea 21 Fostering Outstanding Universities for Research, Team and Integrated Research Institute for Drug Development, College of Pharmacy, Dongguk University, Seoul 02841, Republic of Korea.ORCID 0000-0002-4882-5621
Chang Seong KimBrain Korea 21 Fostering Outstanding Universities for Research, Team and Integrated Research Institute for Drug Development, College of Pharmacy, Dongguk University, Seoul 02841, Republic of Korea.
Peela InduvadanaCollege of Life Sciences and Biotechnology, Korea University, Seoul 02841, Republic of Korea.
Beom Jin ParkDepartment of Radiology, College of Medicine Anam Hospital, Korea University, 73 Goryeodae-ro, Seongbuk-gu, Seoul 02841, Republic of Korea.
Kyeong LeeBrain Korea 21 Fostering Outstanding Universities for Research, Team and Integrated Research Institute for Drug Development, College of Pharmacy, Dongguk University, Seoul 02841, Republic of Korea.
Yongseok ChoiCollege of Life Sciences and Biotechnology, Korea University, Seoul 02841, Republic of Korea.
Jong-Ik HwangDepartment of Biomedical Science, College of Medicine, Korea University, Seoul 73 Goryeodae-ro, Seongbuk-gu, Seoul 02841, Republic of Korea.

Funding

Korea Health Industry Development Institute RS-2022-KH129263National Research Foundation of Korea RS-2023-NR077257, RS-2024-00422678, 2022R1F1A1074216
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acute lung injuryIL-1βinflammasomeLMT2368NLRP3

Identifiers

PMID41155878
PMCPMC12566734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.