Evidence map›Paper›PMID 41155775›Full record

ReviewMedicina (Kaunas, Lithuania)2025

Combined ACL-MCL Injuries: Anatomy, Biomechanics, and Clinical Management.

Riccardo Ghiretti, Francesco Panzavolta, Gian Andrea Lucidi, Stefano Zaffagnini

Abstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Riccardo GhirettiIIa Clinica Ortopedica e Traumatologica, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Francesco PanzavoltaIIa Clinica Ortopedica e Traumatologica, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Gian Andrea LucidiIIa Clinica Ortopedica e Traumatologica, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Stefano ZaffagniniIIa Clinica Ortopedica e Traumatologica, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Combined injuries of the anterior cruciate ligament (ACL) and medial collateral ligament (MCL) represent the most frequent pattern of two-ligament knee injury and pose significant diagnostic and therapeutic challenges. While isolated MCL lesions typically respond well to conservative treatment, persistent medial instability in the setting of ACL-MCL injuries has been associated with increased biomechanical stress on the ACL graft and a higher risk of failure. This review synthesizes current anatomical and biomechanical knowledge of the ACL-MCL complex, exploring therapeutic strategies, ranging from non-operative protocols for selected low-grade lesions to advanced surgical reconstructions tailored to injury severity, location, and associated instability patterns.

Indexed as

Anterior Cruciate LigamentAnterior Cruciate Ligament InjuriesMedial Collateral Ligament, KneeAnterior Cruciate Ligament ReconstructionBiomechanical PhenomenaHumansACLinstabilitykneeMCLmultiligamenttreatment

Identifiers

PMID41155775
PMCPMC12566525

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.