Evidence map›Paper›PMID 41155734›Full record

ArticleMedicina (Kaunas, Lithuania)2025

Phenotypic Expression of Respiratory Diseases and Tailored Treatment in Patients with Intermediate Alpha-1 Antitrypsin Deficiency: Evidence from a Retrospective Analysis of a Selected Cohort of Patients.

Anna Annunziata, Giuseppe Fiorentino, Francesca Simioli, Lidia Atripaldi, Marco Balestrino, Giacomo Zuccarini, Barbara Piras, Alessandro Libra, Fabio Pino, Pierpaolo Di Micco and 6 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Anna AnnunziataRespiratory Pathophysiology and Rehabilitation Unit, Azienda Ospedaliera di Rilievo Nazionale dei Colli, Monaldi Hospital, 80131 Naples, Italy.ORCID 0000-0002-2404-3545
Giuseppe FiorentinoRespiratory Pathophysiology and Rehabilitation Unit, Azienda Ospedaliera di Rilievo Nazionale dei Colli, Monaldi Hospital, 80131 Naples, Italy.
Francesca SimioliRespiratory Pathophysiology and Rehabilitation Unit, Azienda Ospedaliera di Rilievo Nazionale dei Colli, Monaldi Hospital, 80131 Naples, Italy.ORCID 0000-0002-9457-6558
Lidia AtripaldiRespiratory Pathophysiology and Rehabilitation Unit, Azienda Ospedaliera di Rilievo Nazionale dei Colli, Monaldi Hospital, 80131 Naples, Italy.
Marco BalestrinoDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", Azienda Ospedaliera di Rilievo Nazionale dei Colli, Monaldi Hospital, 80131 Naples, Italy.
Giacomo ZuccariniRespiratory Diseases Unit, Ospedale Santo Spirito, 65124 Pescara, Italy.
Barbara PirasRespiratory Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Via San Pietro, 07100 Sassari, Italy.ORCID 0000-0001-5320-5809
Alessandro LibraDepartment of Clinical and Experimental Medicine, Policlinico "G. Rodolico-San Marco", University of Catania, 95123 Catania, Italy.ORCID 0009-0009-7621-3217
Fabio PinoDepartment of Clinical and Experimental Medicine, Policlinico "G. Rodolico-San Marco", University of Catania, 95123 Catania, Italy.
Pierpaolo Di MiccoUOC Medicina Interna, P.O. Santa Maria delle Grazie, Pozzuoli, ASL Napoli2 Nord, 80076 Naples, Italy.ORCID 0000-0002-8484-4598
Carmine SiniscalchiInternal Medicine Department, Parma University Hospital, 43126 Parma, Italy.ORCID 0000-0002-0613-1074
Ilaria FerrarottiDepartment of Internal Medicine and Therapeutics, Pulmonology Unit, University of Pavia, 27100 Pavia, Italy.
Luigi AronneRespiratory Pathophysiology and Rehabilitation Unit, Azienda Ospedaliera di Rilievo Nazionale dei Colli, Monaldi Hospital, 80131 Naples, Italy.
Raffaella ManzoRespiratory Pathophysiology and Rehabilitation Unit, Azienda Ospedaliera di Rilievo Nazionale dei Colli, Monaldi Hospital, 80131 Naples, Italy.
Carlo VancheriDepartment of Clinical and Experimental Medicine, Policlinico "G. Rodolico-San Marco", University of Catania, 95123 Catania, Italy.
Cecilia CalabreseDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", Azienda Ospedaliera di Rilievo Nazionale dei Colli, Monaldi Hospital, 80131 Naples, Italy.ORCID 0000-0003-4293-4461

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

alpha 1-Antitrypsin DeficiencyAdultAgedalpha 1-AntitrypsinCohort StudiesFemaleHumansMaleMiddle AgedPhenotypePulmonary Disease, Chronic ObstructivePulmonary EmphysemaQuality of LifeRetrospective StudiesSurveys and Questionnairesalpha 1-Antitrypsinalpha-1 antitrypsin deficiencyaugmentation therapyintermediate deficiencypulmonary exacerbationquality of liferare AATD variants

Identifiers

PMID41155734
PMCPMC12565761

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.